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Details

VIF World 2025, the Vaccine Innovation Forum, stands as a premier international event dedicated to the advancement of vaccine science and global health. Building on the tremendous success of previous forums, including the groundbreaking VIF World 2024 in Shanghai, this year’s conference aims to further cement its reputation as a crucial meeting place for experts, researchers, policymakers, and industry leaders.


 120+ Speakers

1000+international delegates

30+countries

60+Exhibitors


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Scientific Advisory Board:

Vaccine Innovation Forum World 2025

Vaccine Innovation Forum World 2025

Vaccine Innovation Forum World 2025

Vaccine Innovation Forum World 2025

Vaccine Innovation Forum World 2025

Vaccine Innovation Forum World 2025

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Photos

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Key Sessions & Topics

Novel Vaccine Innovation:

Infectious diseases

RNA Technology

Bacterial vaccines

Veterinary Vaccines

Cancer Vaccines & Immunotherapies

Bioprocessing & Manufacturing

Clinical Trial/Vaccine Safety

Market Access/Regulatory/International Partnership

Adjuvant, Formulation, and Delivery Technologies


Statistics:

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Testimonia:


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Young Scientist Poster Session:

 

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 One-on-One Meeting System:

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1-on-1 Partnering

VIF World-全景.pngJoin us for an exclusive 1-on-1 partnering session at VIF World 2025, where leaders and innovators in the vaccine and biopharmaceutical fields will engage in meaningful discussions. 

This unique opportunity allows participants to delve into emerging trends, share insights, and explore collaborative ventures. Don’t miss the chance to connect with experts and enhance your understanding of the future of vaccine development.

The online system will be available one month before the event date.


Partners

Gold Sponsor

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Silver Sponsor

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Bronze Sponsor

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Conference Bag Sponsor       Cocktail Sponsor

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Exhibitor

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Insert Sponsor 

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Venue

Meeting Venue

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Hotel: Shanghai Marriot Hotel Parkview

Address: 333 Guang Zhong Road West, Jingan District, Shanghai China

Download Hotel reservation form





Schedule
2025-03-20
2025-03-21
2025-03-22
2025-03-20
08:50 -12:00
Main Conference
2025-03-20
08:55-09:00
Opening Remark
Speaker
Vaccine Innovation Forum World 2025
Bin Wang
Founder, Advacccine, China
2025-03-20
09:00-09:45
Plenary Panel: Revolutionizing Global Health: The Future of Vaccine Technology and Innovation
Speaker
Vaccine Innovation Forum World 2025
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK
Vaccine Innovation Forum World 2025
George Fu Gao
Professor, Chinese Academy of Sciences
Vaccine Innovation Forum World 2025
Dan Barouch
Professor, Harvard Medical School
Vaccine Innovation Forum World 2025
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium
2025-03-20
09:45-10:30
Plenary Panel: Global Vaccine Equity: Overcoming Challenges in Distribution and Access
Speaker
Vaccine Innovation Forum World 2025
Rajinder Suri
CEO, DCVMN International, India
Vaccine Innovation Forum World 2025
Hun Kim
President of Global Business, SK Bioscience, South Korea
Vaccine Innovation Forum World 2025
Jing Wang
Board Executive Director, Chief Commercial Officer, CanSino Biologics, China
Vaccine Innovation Forum World 2025
Raman Rao
CEO, Hilleman Laboratories
2025-03-20
10:30-11:00

茶歇

2025-03-20
11:00-11:30
Keynote: Innovative Vaccine Platforms: Accelerating Global Health R&D
Speaker
Vaccine Innovation Forum World 2025
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium
2025-03-20
11:30-12:00

Correlates of Protection for Respiratory Virus Vaccines

Speaker
Vaccine Innovation Forum World 2025
Dan Barouch
Professor, Harvard Medical School
2025-03-20
12:00-13:30
午餐
2025-03-20
13:30 -17:30
Track A: Respiratory diseases/Flu/Covid
2025-03-20
13:30-13:55
Pan-sarbeCoV vaccine: a dream or reality?

The current COVID-19 failed in protection of infection by SARS-CoV-2 variants. It is clear that we need a much better vaccine(s) which has a broad-spectrum protection against the current circulating variants as well as further related viruses.  Learning from the broad immunity observed in SARS survivors who subsequently received COVID-19 vaccine and/or got infected with SARS-CoV-2, we have adopted a cross-clade boosting strategy to develop pan-sarbeCoV vaccines which have demonstrated broad neutralization ability against all current variants as well as sarbeCoVs in clade-1a and clade-2 and -3.

Speaker
Vaccine Innovation Forum World 2025
Linfa Wang
Professor, Duke-NUS Medical School, Singapore
2025-03-20
13:55-14:20
mRNA Vaccines in Low- and Middle-Income Countries: Bridging the Gap
Speaker
Vaccine Innovation Forum World 2025
Kiat Ruxrungtham
Director of Chula Vaccine Research Center, Chulalongkorn University
2025-03-20
14:20-14:45
Impact of glycosylation on a broad-spectrum vaccine against influenza

Influenza epidemics and pandemics caused by newly emerging virus strains highlight an urgent need to develop a universal vaccine against viruses. Previously, a monoglycosylated X-181mg vaccine demonstrated that the HA possessing a single N-acetylglucosamine at each N-glycosylation site is superior to confer broader protection in mice than conventional vaccines. However, the greatest challenge in conducting clinical trials is the need to develop robust manufacturing processes capable of producing vaccines at the pilot scale with the desired stability, potency, and efficacy. Whether the monoglycosylated virus vaccine platform can be applied to the new vaccine strain in a timely manner and whether the mass-produced vaccine has the proper immunogenicity to induce cross-protective immunity remains unclear. Here, we show that a pilot-scale manufacturing process produced a monoglycosylated A/Brisbane/02/2018(H1N1) virus vaccine (IVR-190mg) with a single glycan at each glycosylation site of HA and NA. Compared with the fully glycosylated virus vaccine (IVR-190fg), the IVR- 190mg provided broader cross-protection in mice against a wide range of H1N1 variants. The enhanced antibody responses induced by IVR-190mg immunization include higher hemagglutination-inhibition titers, higher neutralization activity, more anti-HA head domain, more anti-HA stem antibodies, higher neuraminidase activity inhibition titers, and notably, higher antibody-dependent cellular cytotoxicity. Additionally, the IVR-190mg also induced a more balanced Th1/Th2 response and elicited broader splenic CD4+ and CD8+ T-cell responses than IVR-190fg. This study demonstrated that IVR-190mg produced using a pilot-scale manufacturing process elicits comprehensive cross-strain immune responses that have great potential to substantially mitigate the need for yearly reformulation of strain-specific inactivated vaccines.

Speaker
Vaccine Innovation Forum World 2025
JR Chen
COO,RuenHuei biopharma, China
2025-03-20
14:45-15:00
A New Strategy for Vaccine Immune Evaluation System
Speaker
Vaccine Innovation Forum World 2025
Chongyang Liang
Prof., Jilin University;Scientific Advisor, ProMab Forethought;
2025-03-20
15:00-15:30
Reserved by Joinn Lab
2025-03-20
15:30-16:00

茶歇

2025-03-20
16:00-16:25
Decoding Antibody Response to MERS-CoV in Wild Dromedary Camels
Speaker
Vaccine Innovation Forum World 2025
Linqi Zhang
Professor, Tsinghua University
2025-03-20
16:25-16:40
Vaccine Clinical Trials: Practical Insights to Avoid Pitfalls
Speaker
Vaccine Innovation Forum World 2025
Zhaojun Mo
GM, Vaccine Clinical BU at SDM Bioservices / Shanghai SDM, China
2025-03-20
16:40-17:05
Clinical development for RSV vaccine in China
Speaker
Vaccine Innovation Forum World 2025
Wei Tan
SVP, Head of China Research and External Collaboration, Clover Biopharmaceutical, China
2025-03-20
17:05-17:30
Pan-β-coronavirus vaccine development
Speaker
Vaccine Innovation Forum World 2025
Shibo Jiang
Professor, Fudan University, China
2025-03-20
17:30-18:30

Poster Session

2025-03-20
18:30-20:00

Cocktail Party (Invited Only)

2025-03-20
13:30 -17:30
Track B:Cancer Vaccine & Immunotherapy
2025-03-20
13:30-13:55
Immunotherapy for Cancer
Speaker
Vaccine Innovation Forum World 2025
David Weiner
Executive Vice President, The Wistar Institute, USA
2025-03-20
13:55-14:20
Development of mRNA vaccines: from infectious diseases to oncology
Speaker
Vaccine Innovation Forum World 2025
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany
2025-03-20
14:20-14:45
Expanding the Frontier: mRNA Vaccines for Cancer and Autoimmune Diseases(TBD)
Speaker
Vaccine Innovation Forum World 2025
Bo Ying
Founder, CEO, Abogen
2025-03-20
14:45-15:00
SynNeogen: unleash the power of immune system
Speaker
Vaccine Innovation Forum World 2025
Hanxin Lu
Vice President of R&D at Chimigen Biomedical
2025-03-20
15:00-15:25
Precision treatment of pancreatic cancer - personalized tumor treatment vaccine
Speaker
Vaccine Innovation Forum World 2025
Landian Hu
CEO, Anda Biology Medicine Development (Shenzhen) , China
2025-03-20
15:30-16:00
茶歇
2025-03-20
16:00-16:25
Induction of tertiary lymphatic structures (TLS) by a novel immunotherapeutic strategy against solid tumors
Speaker
Vaccine Innovation Forum World 2025
Bin Wang
Founder, Advacccine, China
2025-03-20
16:25-16:50
Innovative Design of mRNA Sequences and Delivery Systems for Therapeutic Cancer Vaccines

1. Clinical Data – Presenting groundbreaking progress in liver cancer treatment, including clinical trial data from the WGc-0201 project, demonstrating its safety, efficacy, and immunogenicity.

2. Platform Technology Highlights – Showcasing WestGene’s proprietary delivery systems and mRNA sequence design, backed by independent intellectual property.

3. Breakthrough Potential – Highlighting the disruptive potential of mRNA technology in tumor immunotherapy.


Speaker
Vaccine Innovation Forum World 2025
Xiangrong Song
Co-Founder, Westgene
2025-03-20
16:50-17:15
A therapeutic cancer vaccine platform enhancing cross-presentation and CD8+ CTL response through targeting dendritic cell cytosol
Speaker
Vaccine Innovation Forum World 2025
Joon Haeng Rhee
Professor, Chonnam National University Medical School, South Korea
2025-03-20
13:30 -17:30
Track C: DCVMN Forum
2025-03-20
13:30-13:55
Strengthening Vaccine Manufacturing Capacity in Developing Countries: The Role of DCVMN
Speaker
Vaccine Innovation Forum World 2025
Rajinder Suri
CEO, DCVMN International, India
2025-03-20
13:55-14:20
Innovative products for low resource settings
Speaker
Vaccine Innovation Forum World 2025
Melanie Saville
CSO, PATH, USA
2025-03-20
14:20-14:45
China Vaccine Industry Overview
Speaker
Vaccine Innovation Forum World 2025
Yuan Yuan
Country Representative, PATH China
2025-03-20
14:45-15:10
BioKangtai’s Strategy and Technology Transfer Practices in the Era of Global Vaccine Cooperation
Speaker
Vaccine Innovation Forum World 2025
Qian Zhang
Director General, International BU, Kangtai Bio
2025-03-20
15:10-15:45
茶歇
2025-03-20
15:45-16:10
Development of the vaccine production facility and tech transfer in Latin America
Speaker
Vaccine Innovation Forum World 2025
Adel Sattarova
Head of Project Management Department, FSUE SPbSRIVS FMBA of Russia
2025-03-20
16:10-16:35
Future prospects for vaccine R&d and manufacturing
Speaker
Vaccine Innovation Forum World 2025
Hun Kim
President of Global Business, SK Bioscience, South Korea
2025-03-20
16:35-17:00
Overview of HPV vaccine development and global vaccine introduction status
Speaker
Vaccine Innovation Forum World 2025
Peter Dull
Deputy Director, Gates Foundation, USA
2025-03-20
13:30 -17:30
Track D: Nasal vaccine and mucosal immunization
2025-03-20
13:30-13:55
Systemic and mucosal immunity: separate roles and cooperation
Speaker
Vaccine Innovation Forum World 2025
Rita Carsetti
VP, IUIS; Prof, Bambino Gesù Children Hospital, Italy
2025-03-20
13:55-14:20
Inhaled Adenovirus (Human type 5) Vectored Tuberculosis Vaccine

Tuberculosis (TB) remains one of the world’s leading causes of death from a single infectious agent, Mycobacterium tuberculosis (Mtb). Despite the wide administration of the Bacille Calmette Guerin (BCG) vaccine, which offers variable, age-dependent protection, the need for a new vaccine effective across all age groups and for population with latent tuberculosis infection (LTBI) is essential for achieving the WHO's End TB Strategy. Recent data suggested that future vaccine designs should prioritize on eliciting lung-localized adaptive immune responses. Promising clinical results from CanSinoBIO’s first-generation TB vaccine, Ad5-Ag85A, highlight the crucial role of mucosal immunity in defending against TB. Currently, CanSinoBIO is in a quick process of the development of the new generation TB vaccine, ADTB, designed as an inhalation booster for individuals immunized with BCG, aiming to prevent new TB infections and the reactivation of LTBI. Utilizing a well-established adenovirus vector, ADTB carries three fused antigens and will be delivered via inhalation, a route successfully employed for CanSinoBIO’s Convidecia AirTM, the world's first inhaled COVID-19 vaccine. Extensive data from clinical trials and post-commercialization studies have proved the safety and efficacy of inhaled Ad5-vectored COVID-19 vaccines. The immunogenicity study of new generation TB vaccine in animal model demonstrated that the lower dose of ADTB can stimulated more robust cellular immune responses locally in the lungs, as well as systemically in the blood and spleen. The protection efficacy results indicated that ADTB effectively inhibits Mtb growth in the lungs and prevents lung damage. Overall, the promising preclinical data encourage further clinical trials of the ADTB vaccine.


Speaker
Vaccine Innovation Forum World 2025
Fang Xu
Sr. Scientist, CanSinoBIO, China
2025-03-20
14:20-14:45
The nose knows why and how

The nose is far more than just a passive tube to get air to the lungs. It serves as a sophisticated and dynamic immune barrier. In this regard, the nose is a critical component of the body's immune defense system, equipped with multiple mechanisms to detect, regulate, and respond to potential threats, thereby playing a vital role in maintaining respiratory health. The nose knows why and how.


Speaker
Vaccine Innovation Forum World 2025
Huimin Yan
Professor, Fudan University
2025-03-20
14:45-15:10
A sequential Intranasal Protein Vaccine Triggers Class Switching from Intramuscularly Primed IgG to Mucosal IgA against SARS-CoV-2

Current intramuscular (IM) COVID-19 vaccines inadequately protect the upper respiratory mucosa. In response, we have developed a nonadjuvanted, interferon-armed SARS-CoV-2 fusion protein vaccine with IM priming and intranasal (IN) boost sequential immunization. Our study shows that this sequential vaccination strategy of the IM+IN significantly enhances both upper respiratory and systemic antiviral immunity in a mouse model, marked by rapid enhancement in systemic and mucosal T and B cell responses, particularly the mucosal IgA antibody response. The IN boost triggers a swift secondary immune response, rapidly inducing antigen-specific IgA+ B cells. Further BCR-seq analysis indicates that these IgA+ B cells primarily arise through direct class switching from pre-existing IgG+ B cells in draining lymph nodes. Notably, our clinical studies reveal that the IN boost after IM vaccination elicits a robust IgA antibody response in humans. Thus, our cytokine-armed protein vaccine presents a promising strategy for inducing rapid and potent mucosal protection against respiratory viral infections.


Speaker
Vaccine Innovation Forum World 2025
Hua Peng
Professor, Guangzhou National Laboratory
2025-03-20
15:10-15:45
茶歇
2025-03-20
15:40-16:05
From Design to lmmunogenicity: An Intranasal Respiratory Syncytial Virus Vaccine Targeting Prefusion F Protein
Speaker
Vaccine Innovation Forum World 2025
Xiawei Wei
Professor, State Key Laboratory of Biotherapy, Sichuan University, China
2025-03-20
16:05-16:30
Swab and Spray: Precision Vaccination with Nasal Vaccines

Respiratory infections begin with invading through the upper respiratory tract. Lessons learned from the SARS-CoV-2 pandemic have shown that higher levels of nasal spike-specific secretory IgA (sIgA) correlate with a lower risk of reinfection. Previously, we found that nasal sIgA is 100 times more potent than serum IgG in neutralizing Omicron subvariants. As mucosal sIgA levels decline over time, then the risk of reinfection increases. Can a nasal vaccine be designed to induce mucosal sIgA? Can the risk of infection be predicted by assessing the level of sIgA in the nasal mucosa? We propose a precision vaccination strategy: a simple self-test strip to monitor sIgA levels using a nasal swab; if the sIgA falls to a low level, a nasal spray of a vaccine can be given. This precision vaccination strategy will provide convenient and effective protection to people in need.


Speaker
Vaccine Innovation Forum World 2025
Ling Chen
PI, Guangzhou Laboratory
2025-03-21
09:00 -12:00
Track D: RNA Tech
2025-03-21
09:00-09:25
Lipid nanoparticles for mRNA vaccine delivery
Speaker
Vaccine Innovation Forum World 2025
Norbert Pardi
Associate Professor, University of Pennsylvania, USA
2025-03-21
09:25-09:50
Advanced quality control strategies for mRNA vaccines

Lipid nanoparticles (LNPs) comprising mRNA are applicable as vaccines but also for a scope of therapeutic purposes. Despite of several initiatives to align on standard panels for quality assessment of such mRNA vaccines, discussions for identifying best and appropriate control strategies are still ongoing. So far, the focus has been mostly on the properties of the molecular properties of the individual components (like identity, content, integrity).

However important quality-related aspects of such mRNA vaccines derive from their colloidal nature. They are intrinsically polydisperse, multicomponent systems, formed by self-assembly between the respective moieties. Size dependent structural properties, drug loading and local chemical-physical coherencies inside the particles should be addressed.

In this presentation, biophysical approaches to get better insight into such chemical-physical properties with relevance for quality of the mRNA LNPs are presented.


Speaker
Vaccine Innovation Forum World 2025
Heinrich Hass
CTO, NeoVAC, UK
2025-03-21
09:50-10:05
Formulation research and development of mRNA therapeutics based on stability, safety and accessibility
Speaker
Vaccine Innovation Forum World 2025
Yafei Li
R&D Director, Rhegen Biotech, China
2025-03-21
10:05-10:30
RNA platform implementation in Brasil: Seeding the innovation ecosystem in Latin America
Speaker
Vaccine Innovation Forum World 2025
Patrícia Neves
Project Manager, mRNA center,Bio-Manguinhos/ Fiocruz, Brazil
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
mRNA vaccines and global health: addressing global unmet needs in infectious diseases
Speaker
Vaccine Innovation Forum World 2025
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany
2025-03-21
11:25-11:40
Comprehensive LNP Characterization from Cargo to Target Modification by Nano-Flow Cytometry

Analyzing Lipid-based Nanoparticles (LNPs) as vectors presents various technical challenges stemming from their complex structure, small size, and encapsulation efficiency. Successfully evaluating the loading ratio and RNA distribution within these particles is crucial for identifying high-quality candidates and optimizing formulation strategies to minimize waste.

The NanoAnalyzer offers a comprehensive solution to overcome the hurdles inherent in LNP analysis. NanoFCM has demostrated the effectiveness of nFCM analysis in addressing the complicated challenges of LNP characterization, including efficacy of nanoparticle loading, mRNA quantification, and the surface density of various targeting modalities.


Speaker
Vaccine Innovation Forum World 2025
Na Wang
Application Engineer, NanoFCM
2025-03-21
11:40-11:55
Process Development for Circular RNA: Advancing Manufacturing Strategies
Speaker
Vaccine Innovation Forum World 2025
Kaiyao Wei
Process Scientist,YXgene
2025-03-21
11:55-12:15
Engineering Internal Architecture of Lipid Nanoparticles to Promote Efficient mRNA Endosomal Release

Lipid nanoparticles (LNPs) are the cornerstone of non-viral mRNA delivery systems, yet their therapeutic potential remains constrained by inefficient endosomal escape, with cytoplasmic delivery rates as low as 2%. Traditional approaches to enhancing endosomal release have primarily focused on chemical modifications of ionizable lipids. Here, we introduce a novel strategy centered on engineering the internal architecture within core-shell LNPs to substantially improve mRNA delivery efficiency. By utilizing ionizable lipid-coated gold nanoparticles (AuNPs) as a demonstrative core, we systematically optimized the LNP nanostructure, achieving a twofold increase in endosomal escape efficiency and a 100-fold enhancement in mRNA diffusion within the cytoplasm compared to conventional LNPs. This structural optimization also promotes more uniform and stable nanoparticle

assembly. In vitro studies demonstrated higher mRNA expression and transfection efficiency in HeLa and 293 cells treated with engineered core-shell LNPs. In vivo evaluations revealed a nearly fivefold increase in mRNA expression in murine models, alongside enhanced immunogenicity in SARS-CoV-2 spike-mRNA vaccines and therapeutic efficacy in a triple-negative breast cancer model. Comprehensive biocompatibility and biosafety assessments confirmed the favorable safety profile of the engineered LNPs. This internal architecture optimization framework provides a scalable and adaptable pathway for advancing mRNA therapeutics and vaccines, addressing a key bottleneck in endosomal release and paving the way for broader biomedical applications.

Speaker
Vaccine Innovation Forum World 2025
Yuhong Cao
PI, the National Center of Nanoscience and Technology, China
2025-03-21
12:30-13:30
午餐
2025-03-21
09:00 -12:00
Track C: Vaccine Design
2025-03-21
09:00-09:25
AI-Guided and Structure-Based Vaccine Design
Speaker
Vaccine Innovation Forum World 2025
George Fu Gao
Professor, Chinese Academy of Sciences
2025-03-21
09:25-09:50
Structure-Based Vaccine Design: Innovations in Stabilizing Antigens and Addressing Emerging Viral Threats
Speaker
Vaccine Innovation Forum World 2025
Shaowei Li
Professor, Xiamen University
2025-03-21
09:50-10:15
Proteolysis-Targeting Live Vaccine Technologies

The usefulness of live attenuated virus vaccines has   been limited by suboptimal immunogenicity, safety concerns or cumbersome   manufacturing processes and techniques. We developed proteolysis-targeting   (PROTAR) vaccine technologies by using the host cell’s ubiquitin–proteasome   system to manipulate stabilization and degradation of viral proteins of   influenza viruses. We engineered the genome of influenza viruses in stable   cell lines engineered for virus production to introduce proteasome-targeting   domain(s), generating fully infective PROTAR viruses that were live   attenuated by the host protein degradation machinery upon infection. In mouse   and ferret models, PROTAR viruses were highly attenuated and able to elicit   robust and broad humoral, mucosal and cellular immunity against homologous   and heterologous virus challenges. The PROTAR vaccine approaches may be   broadly applicable for generating live attenuated vaccines.

Speaker
Vaccine Innovation Forum World 2025
Longlong Si
Professor, Shenzhen Institute of Advanced Technology, CAS, China
2025-03-21
10:15-10:30
Bioassay for vaccine efficacy
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
AI-assisted vaccine and adjuvant design by immunoswithing technology
Speaker
Vaccine Innovation Forum World 2025
Ken Ishii
Director, International Vaccine Design Center, Professor, University of Tokyo, Japan
2025-03-21
11:25-11:50
Characterization of structural biology and immunology of virus-like structure vaccine
Speaker
Vaccine Innovation Forum World 2025
Qihan Li
Professor, Weirui Bio, China
2025-03-21
11:50-12:15
A path toward broadly and durably protective vaccines
Speaker
Vaccine Innovation Forum World 2025
Yoshimasa Takahashi
Director,National Institute of Infectious Diseases, Japan
2025-03-21
09:00 -12:00
Track B:Emerging & Re-emerging Diseases
2025-03-21
09:00-09:25
Malaria Vaccines: from Licensure to Elimination

-       Overview of new high efficacy licensed R21/MM malaria vaccine

-       Next steps for Oxford – SIIPL multi-stage malaria vaccines

-       The road to elimination and eradication with new high-efficacy malaria vaccines


Speaker
Vaccine Innovation Forum World 2025
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK
2025-03-21
09:25-09:50
Rational design of Zika vaccine to eliminate dengue enhancement
Speaker
Vaccine Innovation Forum World 2025
Lianpan Dai
Principle Investigator, Institute of Microbiology, CAS, China
2025-03-21
09:50-10:15
Innovative immunogen design for mpox virus vaccine development

The   worldwide outbreak of mpox virus (MPXV) in 2022 and the emergence and spread   of a new strain, clade Ib, in Africa in 2024 highlight the threat of a   sustained global epidemic of MPXV; however, the existing vaccines, attenuated virus   vaccine and replication-deficient virus vaccine, have raised concerns about   either their safety or efficacy. By using a structure-guided multi-antigen   fusion strategy, we design a ‘two-in-one’ immunogen, DAM, containing the   single-chain dimeric MPXV extracellular enveloped virus antigen A35   bivalently fused with the intracellular mature virus antigen M1. DAM   preserved the natural epitope configuration of both components and resulted   in stronger A35-specific and M1-specific antibody responses and more robust   neutralizing antibody titers than either co-immunization strategy or live   virus vaccination, collectively conferring effective in vivo protection from   MPXV challenge. Moreover, DAM showed comparable systemic immune responses and   in vivo protection with iteratively designed quadrivalent-chimeric immunogens,   demonstrating the superiority of the design. Finally, faster tissue virus   clearance was observed in the live virus vaccine-immunized group, accompanied   by severe non-infectious tissue damage, suggesting a redundant immune   response. We therefore propose a safer profile for protein vaccines than for   live virus vaccines, again due to precise and effective immunization. These   findings provide innovative insights and a promising vaccine candidate for   the development of alternative vaccines against MPXV and other   orthopoxviruses.

Speaker
Vaccine Innovation Forum World 2025
Han Wang
Associate Professor, Peking University
2025-03-21
10:15-10:30
Harnessing Opportunities: Unlocking the Potential for Clinical Trials in Africa
Speaker
Vaccine Innovation Forum World 2025
Christopher Obwanga
East Africa Regional Manager, P-95, Nigeria
2025-03-21
10:30-11:00
茶歇
2025-03-21
11:00-11:25
Efficacy safety and immunogenicity of hexavalent rotavirus vaccine in China
Speaker
Vaccine Innovation Forum World 2025
Gelin Xu
Senior expert,Wuhan Institute of Biological Products ltd co.
2025-03-21
11:25-11:50
Assembly of Virus-like Particles Harnessed with RNA-based Chaperone

Assemblages   of key immunologic features of viruses as highly repetitive particulate   structures are essential for inducing potent and long-lasting antibody   responses. Capitalizing on a novel function of RNAs as chaperone (Chaperna),   here we provide a robust protein folding vehicle that could be implemented   for virus-like particle (VLP) or nanoparticle (NP) assemblies in bacterial   host. Here, tRNA functions as a ‘pace-maker’ for the assembly by controlling   the overall kinetic network of antigen folding pathway into immunologically   relevant conformation. Proof-of-concept was established for variety of NP   vaccines, including H5N1 influenza, RSV, Dengue fever, West Nile, Japanese   Encephalitis, VLP vaccines for Norovirus and subunit vaccine against   pertussis. The Chaperna platform enables bacterial production and delivery of   low-cost vaccines as a high-priority vaccine strategy against emerging and   re-emerging viral infections.

Speaker
Vaccine Innovation Forum World 2025
Baik-Lin Seong
Director General, Vaccine Innovative Technology ALliance (VITAL)-Korea
2025-03-21
11:50-12:15
A quadrivalent mRNA vaccine candidate elicited potent immune responses against monkeypox virus and protection in a rodent model

The global outbreak of the 2022 monkeypox virus (Mpox) infection of humans raised public health concerns about the threat of human-to-human transmission of zoonotic diseases and the recent escalating outbreak of the deadly clade 1b Mpox in Africa triggered the declaration of a global public health emergency. At present, there is an unmet need to contain the outbreak due to some serious adverse reaction of the existing vaccines, to be confirmed efficacy against Mpox in at-risk populations and constrained vaccine supply. Development of a safe, more effective and scalable vaccine against Mpox is imminent to address this continental and global health crisis as quickly and equitably as possible. We have developed a novel mRNA vaccine candidate expressing four vaccinia viral antigens A27, L1, A33, and B5 in tandem in one molecule and evaluated the vaccine immunogenicity in rodent models. Immunization of animals with the candidate mRNA vaccine induced a potent cellular immune response and long-lasting antigen-specific binding antibody and neutralizing antibody responses in rodents. Strikingly, the neutralizing antibody responses against vaccinia virus (VACV) and Mpox were significantly stronger than the existing live attenuated vaccine. The mRNA vaccine completely protected mice from VACV induced fatality and significantly reduced pulmonary viral load and histopathology induced by VACV challenge. From a manufacturing perspective, the novel design of the mRNA vaccine facilitated a simplified manufacturing process with reduced cost but increased product competitivity. The results hold promise for this mRNA vaccine candidate to be used for protection of human in a Mpox pandemic.

Speaker
Vaccine Innovation Forum World 2025
Yelin Xiong
VP, Yither Biotech Shanghai/Zhonghui Yuantong Bio Jiangsu, China
2025-03-21
09:00 -12:00
Track A: AMR& Biomanufacturing
2025-03-21
09:00-09:25
The urgent need for new combination vaccines

The vaccination schedule has grown increasingly crowded, particularly for infants

Lack of space makes it challenging or impossible to introduce new life-saving vaccines

Combination vaccines may help by reducing crowding while reducing vaccine hesitancy

Challenges include formulation design, regulatory pathways, and how best to value combinations


Speaker
Vaccine Innovation Forum World 2025
Christopher Gill
Senior Program Officer, Vaccine Clinical Developmenta Gates Foundation, UK
2025-03-21
09:25-09:50
Rational design and generation of a noval recombinant Pseduomonas areaginosal subunit vaccine
Speaker
Vaccine Innovation Forum World 2025
Jiang Gu
Professor, Vice Director, Army Medical University
2025-03-21
09:50-10:20
TBD-Wuxi Vaccines
2025-03-21
10:15-10:35
Harnessing mRNA Technology to Combat Antimicrobial Resistance: Pioneering Vaccines for Drug-Resistant Bacteria
Speaker
Vaccine Innovation Forum World 2025
Caiyi Fei
Co-founder& VP, Therarna
2025-03-21
10:35-11:00
茶歇
2025-03-21
11:00-11:25
Isolation of protective monoclonal antibodies and development of novel fusion protein vaccines against tuberculosis

Tuberculosis (TB) is the oldest and most deadly pandemic in history, still causing about 1.3 million deaths in 2022. BCG vaccination in humans results in the production of functional antibodies and long-lived memory B cell responses. We have showed that antibodies taken from protected healthcare workers (ie. individuals who were highly exposed to Mtb but remained uninfected) and transferred into mice could protect those mice against Mtb infection. It remains unknown which Mtb or BCG antigens induce protective antibody responses and what the mechanisms of such protective antibodies may be. In this study, two combinational antibody isolation methods were used to isolate the monoclonal antibodies against BCG/Mtb antigens. By the first method, the known protective antigens were used for mAbs isolation by single B cell isolation and Hybridima techniques, and the specific mAbs were isolated and the protective mAbs were identified by ex vivo and in vivo assay. By another method, the whole bacteria and the outer-membrane proteins of BCG were used, and then the B cells or the hybridoma technology was used to select the antibodies targeting the antigens. The protective functional activity of these mAbs were evaluated by using ex vivo and in vivo M.tb infection models, and the protective antigens were identified and used for the subunit vaccines development, which have shown protection in the mouse model. This research will promote a better understanding of host protective immune responses and the rational approach for the development of novel and effective TB vaccines.


Speaker
Vaccine Innovation Forum World 2025
Hao Li
Associate Professor, China Agricultural University
2025-03-21
11:25-11:55
More than a theory - Successful vaccination by Micro Array Patches
Speaker
Vaccine Innovation Forum World 2025
Markus Winterberg
Head, Analytical Development, Microbiology, Quality Control – MAP Program, LTS, Germany
2025-03-21
11:55-12:10
A High-Density Microarray Patch (HD-MAP) to Improve Effectiveness of Vaccines
Speaker
Vaccine Innovation Forum World 2025
Thomas Lake
SVP Vaccine Alliances, Vaxxas, Autralia
2025-03-21
13:30 -17:30
Track D: RNA Tech
2025-03-21
13:30-13:55
Mechanisms of vaccine reactogenicity

·         Overview of what is known about local and systemic symptoms post vaccination. Ex of adjuvanted and mRNA vaccines

·         Recent data at University of Geneva on mechanisms of reactogenicity of mRNA vaccines in humans and mouse models (collaboration with Moderna)

·         Key message: both vaccine-specific and host intrinsic factors contribute to reactogenicity

·         Perspectives for the development of improved vaccines


Speaker
Vaccine Innovation Forum World 2025
Arnaud Didierlaurent
Assistant Professor, Director of Center of Vaccinology,University of Geneva
2025-03-21
13:55-14:20
Revolutionizing Therapeutics with Next-Generation RNA Platforms: From Vaccines to Gene Therapy (TBD)
Speaker
Vaccine Innovation Forum World 2025
Zihao Wang
CEO, Immorna Biotherapeutics
2025-03-21
14:20-14:45
Rational design of ionizable lipids for RNA delivery
Speaker
Vaccine Innovation Forum World 2025
Xuexiang Han
Professor, SIBCB, China
2025-03-21
14:45-15:00
Scaling Up the Next RNA Frontier: Strategy & Innovations in Large-Scale circRNA Manufacturing
Speaker
Vaccine Innovation Forum World 2025
Yongbo Xue
Senior Research Scientist, BiosynRNA Biotechnology
2025-03-21
15:00-15:15
Non-reactogenic LNPs addressing mRNA vaccination hesitancy

mRNA vaccines have revolutionized the response to infectious diseases, as demonstrated during the COVID-19 pandemic. However, these vaccines face significant challenges, including suboptimal delivery efficiency and high reactogenicity, leading to reduced vaccine acceptance. Our preliminary studies show that General Therapeutics' Next-generationiLDC LNPs can reduce pro-inflammatory cytokine levels by 50% and enhance mRNA expression up to 8-fold compared to traditional formulations, and more importantly being 70% less pain and tissue damage. mRNA vaccines formulated with our iLDCs will improve efficacy and reduce adverse reactions. Our LNP technology has the potential to significantly improve the safety and effectiveness of mRNA vaccines. By overcoming the limitations of current mRNA vaccines, this project aims to enhance vaccine safety and efficacy, addressing mRNA vaccination hesitancy, ultimately contributing to better global health outcomes.

Speaker
Vaccine Innovation Forum World 2025
Jiangsheng Xu
Founder& CSO, General Therapeutics, USA
2025-03-21
15:15-15:35
茶歇
2025-03-21
15:35-16:00
Pre-clinical development of a circular RNA vaccine against Nipah virus

Circular RNA (cRNA) vaccine is a promising alternative to the canonical linear RNA vaccine. Compared to linear RNA, cRNA has a longer half-life and could potentially be more thermostable and does not require extreme storage and transportation temperature. The goal of this study is to evaluate this novel cRNA platform through the development of a vaccine against Nipah virus. We assessed various cRNA encoding for the full-length (NiV-FL) or only the ectodomain of Nipah glycoprotein G in vivo and found that one of the cRNA-NiV-FL elicited better antibody and neutralizing antibody responses in a dose-dependent manner. Next, we evaluated the effect of various LNP for encapsulation of the cRNA in vivo and found that all of the novel LNP-encapsulated cRNA elicited higher antibody response in mice when compared to a clinically approved LNP. In conclusion, we have successfully performed preclinical proof of concept of a cRNA vaccine against Nipah. Future experiments involved further development of this cRNA vaccine into a viable and cost-efficient vaccine product.

Speaker
Vaccine Innovation Forum World 2025
Pei-Yin Lim
Senior Manager, Preclinical R&D, Hilleman Laboratories, Singapore
2025-03-21
16:00-16:25
Optimizations of VZV mRNA vaccine

We have successfully developed a sophisticated VZV mRNA vaccine by optimizing its antigen truncation, RNA sequence, and vaccination approach. Our study demonstrates that the RNA sequence optimized Full-length gE protein inoculated intradermally executes a better immunogenicity.


Speaker
Vaccine Innovation Forum World 2025
Wenshuo Zhou
Leading Scientist & CSO Academic Secretary, CNBG- Virogin Biotech, China
2025-03-21
16:25-16:50
Optimizing Tissue Distribution & Safety of LNP-Mediated Prophylactic Vaccines to Accelerate Prevention of Infection & Disease

The talk begins by detailing the robust immunogenic responses triggered by Innonra’s mRNA vaccines, which serve as a cornerstone for their preclinical efficacy. This discussion was intricately linked to how our cutting-edge lipid nanoparticle (LNP) technology precisely directs these vaccines to targeted tissues, significantly enhancing their effectiveness. Moreover, this technology not only boosts vaccine performance but also plays a crucial role in improving safety profiles. These innovations mark a significant step forward in our ability to combat infectious diseases with safer and effective vaccine solutions.

Speaker
Vaccine Innovation Forum World 2025
Hui Li
R&D Director, Innorna
2025-03-21
13:30 -17:30
Track C: Vaccine Tech Innovation
2025-03-21
13:30-13:55
Innovative Delivery Methods for Next-Generation Vaccines: Nasal, Inhalable, and Beyond

The development of next-generation vaccines has opened new frontiers in immunization strategies, particularly through innovative delivery methods such as nasal sprays and inhalable formulations. These novel approaches offer significant advantages over traditional injection-based vaccines, including improved patient compliance, enhanced immune responses, and the potential for rapid mass immunization during pandemics. Nanotechnology plays a crucial role in these advancements by enabling the creation of nanoparticle-based vaccines. These nanoparticles can serve as carriers for antigens, enhancing the delivery and stability of vaccines. They can also act as adjuvants, boosting the immune response by targeting antigen-presenting cells more effectively12. This presentation will explore the latest advancements in vaccine delivery technologies, focusing on the mechanisms, benefits, and challenges associated with nasal and inhalable vaccines, as well as the integration of nanotechnology. Additionally, we will discuss the implications of these innovations for global health, particularly in low-resource settings, and the future directions for vaccine research and development.

Speaker
Vaccine Innovation Forum World 2025
SeyedReza Banihashemi
Director of R&D, Razi Vaccine & Serum Research Institute
2025-03-21
13:55-14:20
The Molecular Clamp Platform: A broadly applicable solution to the manufacture of multivalent subunit vaccines for respiratory viruses

Respiratory syncytial virus (RSV), human metapneumovirus (hMPV) and parainfluenza virus 3 (PIV3) are medically important causes of respiratory tract infections. Combined these three viruses cause more severe disease and hospitalisations than influenza viruses. After more than 5 decades of unsuccessful research and development, vaccines have recently been approved for the prevention of lower respiratory tract disease caused by RSV, however vaccines for hMPV and PIV3 remain in early-stage development. The game changing development which lead to effective RSV vaccines has been discovery of methods to stabilize the RSV fusion glycoprotein (F) into the elusive prefusion conformation (preF).

The University of Queensland has developed a broadly applicable proprietary technology (molecular clamp), to facilitate preF stabilization not only for RSV but also hMPV and PIV3, and a diverse array of fusion glycoproteins from other viral families. In association with biotech spinout company, Vicebio Ltd, our team have identified lead candidate subunit vaccines for RSV, hMPV and PIV3, all of which have demonstrated, high yield, high stability and the ability to effectively elicit strong neutralizing immune response in animal models. The bivalent vaccine against RSV and hMPV (VXB-241) entered a phase I clinical trial in August 2024 and the trivalent formulation which also includes PIV3 (VXB-251) is completing pre-clinical development.

With three separate respiratory virus vaccines currently recommended for elderly populations (seasonal influenza, COVID-19 and RSV), the prospect of adding further vaccines for other high burden respiratory viruses such as hMPV or PIV3 into the schedule becomes problematic. Vicebio seeks to overcome this problem through the production of highly protective, multivalent vaccines in ready-to-use, liquid-stable formulations.


Speaker
Vaccine Innovation Forum World 2025
Keith Chappel
Group Lead, The University of Queensland, Australia
2025-03-21
14:20-14:45
An economical adjuvant without production limit to induce potent cell-mediated immunity in subunit vaccines

Compared with humoral immunity which blocks pathogen infection, cell-mediated immunity (CMI) clears infected cells to limit the replication and spread of pathogens. This increases vaccine efficacy against highly contagious (e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) or latent (e.g., herpesvirus) pathogens. Although FDA-approved AS01B, AS01E and matrix-M adjuvants can induce potent CMI in subunit vaccines, they rely on QS21, a polysaccharide extracted from the bark of Quillaja saponaria. Because massive synthesis of QS21 is infeasible and Q. saponaria occurs only in South America, the supply of these CMI-inducing adjuvants is limited (e.g., approximately 20 million doses annually for AS01B), resulting in higher prices for the corresponding vaccines (approximately 150-200 USD per dose of ShingrixTM compared with other vaccines normally sold at 10-40 USD per dose).

The FDA has recently approved ionizable lipid nanoparticles (LNPs) for COVID-19 mRNA vaccines as carriers and oligodeoxynucleotides containing CpG motifs (CpG ODNs) for hepatitis B subunit vaccine as immunostimulators, both could be synthesized economically. We developed a novel LNP-CpG ODN adjuvant and tested its potency in different subunit vaccines. In varicella-zoster virus (VZV) vaccines, which use glycoprotein E as an antigen, this vaccine induced levels of CMI, which plays a decisive role in the efficacy of zoster vaccines, comparable to those of ShingrixTM in a VZV-primed mouse model that was adopted for preclinical studies of ShingrixTM and in non-human primates. In addition to potent humoral responses (approximately 10 times greater than those induced by alum adjuvants after 2 injections), Th1-oriented CMI was induced in respiratory syncytial virus (RSV) vaccines via the use of stabilized fusion glycoprotein (F) as an antigen, which may be helpful for lowering the risk of antibody-dependent enhancement of immunopathology. For rabies virus (RABV) vaccines, the surface glycoprotein (RABV-G) was used as an antigen, and IgG antibodies were induced within 7 days of primary vaccination (compared with 14 days with alum as an adjuvant). Prompt-induced humoral immunity and potent CMI that are helpful for eradicating infected viruses may work synergistically for increasing RABV vaccine efficacy.

In conclusion, LNP-CpG ODN adjuvants are helpful for inducing prompt, potent humoral immunity and potent CMI for subunit vaccines


Speaker
Vaccine Innovation Forum World 2025
Cunbao Liu
Professor, Institute of Medical Biology, CAMS&PUMC, China
2025-03-21
14:45-15:10
Amezosvatein Phase 2 trial results
Speaker
Vaccine Innovation Forum World 2025
George Simeon
CEO, Curevo Vaccine
2025-03-21
15:10-15:35
茶歇
2025-03-21
15:35-16:00
Innovating Plant-Based Vaccines: A New Frontier in Global Health

As the global demand for rapid, scalable, and cost-effective vaccine production grows, Baiya Phytopharm has emerged as a leader in plant-based vaccine technologies. Our novel vaccine platform harnesses the power of plants to produce vaccines faster and more sustainably than traditional methods. This presentation will showcase the science behind Baiya's platform, including its speed, scalability, and potential to address pandemics and rare diseases. We will also discuss our latest achievements, such as the development of COVID-19 vaccine candidates, and explore the future of plant-based biologics in global healthcare.

Speaker
Vaccine Innovation Forum World 2025
Suthira Taychakhoonavudh
CEO, Baiya Phytopharm, Thailand
2025-03-21
16:00-16:25
Revolutionizing Pneumococcal Vaccination: Advancing Towards a Universal Pneumococcal Vaccine Solution
Speaker
Vaccine Innovation Forum World 2025
Tim Hirst
Chairman & CEO, GPN Vaccines
2025-03-21
16:25-16:50
Vaccine development based on DDS technology

I would like to discuss the vaccine technologies for nasal vaccine and mRNA vaccine.

Speaker
Vaccine Innovation Forum World 2025
Yasuo Yoshioka
Project Leader, BIKEN Center for Innovative Vaccine Research and Development, Japan
2025-03-21
13:30 -17:30
Track A: Biomanufacturing& Formulation
2025-03-21
13:30-13:55
Nanotechnology in Vaccine Development: Transforming Delivery and Efficacy
Speaker
Vaccine Innovation Forum World 2025
Chunying Chen
Academician, Professor, The National Center for Nanoscience and Technology,CAS, China
2025-03-21
13:55-14:20
Empowering the Immunity: CpG adjuvants for vaccine development and cancer therapy

This talk will discuss the TLR9 pathway and novel CpG candidates that ParrBio has developed to unleash the potential of innate immune system to fight infectious diseases and cancer. We have shown that the novel type of CpGs can stimulate both humoral and cellular immunity and possess distinct characteristics comparing with the CpGs on the market. These novel types of CpGs have shown superiority when used as vaccine adjuvants and demonstrated potent anti-tumor activity in both animal models and in cancer patients. ParrBio is actively seeking global partners to advance its CpG compounds in vaccine development and cancer therapeutic drug application.


Speaker
Vaccine Innovation Forum World 2025
Jon Wang
R&D President / CSO,Parr Biotechnology
2025-03-21
14:20-14:50
Next Generation of Highly Effective Adjuvant Systems: Safe & Efficacious Vaccines Made Possible Through Partnerships, with Inimmune and SPI Pharma

Vaccines have a long history as one of the most effective methods for the prevention of infectious diseases, but a lack of approved vaccine adjuvants hinders the development of efficacious subunit vaccines. The impact of the vaccine adjuvant AS01 on the efficacy (97%) of the Shingrix vaccine is an excellent example of what can be achieved with the optimal combination of recombinant antigen and adjuvant system.   While a vaccine must be efficacious, an ideal vaccine should also be relatively easy to manufacture and stable within the existing supply chain in order to improve availability to both the developing and developed world.   Our team has developed several 3rd generation pattern recognition receptor agonists capable of being formulated with a wide variety of vaccine delivery systems (emulsions, liposomes, inorganic nanoparticles, etc.) providing a deep toolbox to enable the optimal pairing of adjuvant and antigen. In the work presented here, we evaluated recombinant A/Victoria/2009 monovalent detergent split influenza antigen in combination with our novel toll-like receptor agonist INI-2002 in combination with QS21 saponin in our AS01-like formulation called T4Q, administered intramuscularly. T4Q induces Th1-biased antigen-specific antibody and T cell responses similar to commercial AS01. Additionally, T4Q adjuvanted vaccination provides protection from heavily drifted influenza challenge that is 100% lethal after vaccination with antigen only. In our novel model for measuring injection site pain, T4Q does not demonstrate increased injection site pain compared to AS01. Having validated this injection site pain model will enable us to evaluate novel formulations in an effort to reduce injection site pain.

Speaker
Vaccine Innovation Forum World 2025
Juhienah Khalaf
Director of Chemistry, Inimmune Corp
2025-03-21
14:50-15:05
Enhancing Mucosal Immunity with RAR Agonists as Potent Vaccine Adjuvants
Speaker
Vaccine Innovation Forum World 2025
Haibo Li
Professor, Army Medical University, China
2025-03-21
15:05-15:35
茶歇
2025-03-21
15:35-16:00
Harnessing the power of TLR agonists as vaccine adjuvants

Until recently, development of new human adjuvants was held back by poor understanding of their mechanisms of action and associated safety concerns. Major investment has led to renewed activity in the adjuvant field, resulting in multiple new adjuvant discoveries. Vaxine has successfully developed an extensive range of new vaccine adjuvants including polysaccharides (delta inulin), various small molecule and oligonucleotide agonists of toll-like receptor (TLR)-2, 4, 7, 9 and NOD2, many identified and optimised using our AI-based in silico high throughput drug screening approach - our experience in use of AI for immunomics research dating back over 25 years when Professor Petrovsky was a founder of the field of Immuno-informatics.  These adjuvants alone and in combination can be used to tailor the immune response in any direction to get the desired outcome. However, adjuvants are just one piece of a successful vaccine, the other two pieces being the antigen platform and the delivery system. Vaxine has invested in optimizing each of these elements. It is utilising high yielding low-cost insect cell and C1 fungal protein expression platforms to produce its protein antigens, combining these with its proprietary adjuvants and then utilizing novel delivery systems including needle-free jet injectors, microneedle transdermal patches, aeosol lung delivery and intra-oral mucosal administration to ensure these are delivered to the right compartments to deliver a protective vaccine response. On top of this it is using AI to help speed the discovery and design of new antigens and adjuvant to feed this pipeline. This demonstrates major benefits in respect of enhanced protection when co-formulated with respiratory vaccines in animal models of influenza, SARS-CoV and tuberculosis, amongst many others. These adjuvants also have major effects on cellular and in particular, CD8 T cell immunity, with important implications for use in viral but also in cancer vaccines where induction of cytotoxic T cells is paramount. Thus the robust protection against respiratory pathogens afforded by these adjuvants when formulated with appropriate antigens can be ascribed to their ability to broadly enhance all arms of the adaptive immune response, resulting in generation of high avidity antibody and memory B cells as well as memory and effector CD4 and CD8 T cells.

Speaker
Vaccine Innovation Forum World 2025
Nikolai Petrovsky
Founder, Vaxine, Australia
2025-03-21
16:00-16:15
Reserved by Adjane, Netherlands
2025-03-21
16:15-16:40
Nanoemulsion Adjuvants

The recombinant protein/polypeptide vaccine has become a new generation of vaccine technology, which will be widely used in the prevention and treatment of infectious diseases and tumors. However, the recombinant proteins/peptides need to be matched with appropriate adjuvants to become a valuable vaccine with especially cellular immunity. Adjuvants are a class of non-specific immune enhancers that can enhance the immunogenicity of antigens and change the type of immune response. The most widely used Alum adjuvants have good efficacy in increasing antibody immunity but are less effective in novel vaccines that require cellular immunity, such as tumor vaccines. In recent years, several novel innate immune agonists have been used in clinical trials for preventive and therapeutic vaccines. For example, the AS01 adjuvant developed by GSK, which combines two classes of agonists -MPLA and QS21- lipid nanoparticles, is successfully applied to the herpes zoster vaccine in 2018. Therefore, new adjuvants have become the core technology of the development pipeline of vaccine companies. Here, I will present our effort to develop new adjuvant formulation as nanoemulsion. We have obtained new nanoparticulate adjuvants without GS21 by using efficient agonists and formulation technique. The performance adjuvanted with antigens of VZV, Flu, RSV shows excellent antibody and cellular immunity with good safety. 


Speaker
Vaccine Innovation Forum World 2025
Yongming Chen
Professor, Sun Yat-sen University
2025-03-21
16:40-17:05
Engineered design of aluminum-based combination adjuvants

Abstract: The development of high-purity antigens highlights the urgent need for novel adjuvants capable of triggering robust immune responses. Aluminum salts (Alum) are often employed as adjuvants but yield limited cellular immune responses. To address this limitation, Toll-like receptor (TLR) agonists have been utilized in combination with Alum. However, the current use of Alum and TLR agonists remains restricted to linear mixtures, and the interaction mechanism between TLR agonists and Alum is not well understood. In our study, we formulated combination adjuvants using aluminum oxyhydroxide nanorods (AlOOH NRs) and TLR agonists, such as CpG and Poly(I:C). The engineered combination adjuvants induce enhanced humoral and cellular immune responses in several antigen models, including HBsAg virus-like particles (VLPs), human papillomavirus (HPV) VLPs, and varicella-zoster virus (VZV) glycoprotein E (gE). Further mechanistic studies show that the formulation of combination adjuvants, such as the conjugation method, the orientation of the CpG molecule, and the molecular weight (MW) of Poly(I:C), determines the physicochemical properties and adjuvanticity of these combination adjuvants. Our study offers insights into adjuvant design to meet the formulation requirements for both prophylactic and therapeutic vaccines.


Speaker
Vaccine Innovation Forum World 2025
Bingbing Sun
Professor, Dalian University of Technology, China
2025-03-21
13:30 -17:30
Track B: Clinical Development & Partnership
2025-03-21
13:30-13:55
Clinical data of single dose vaccine development for Rabies
Speaker
Vaccine Innovation Forum World 2025
Sandy Douglas
Associate Professor, Oxford University, UK
2025-03-21
13:55-14:20
Efficacy and safety of a herpes zoster vaccine in clinical trial in China
Speaker
Vaccine Innovation Forum World 2025
Jingxin Li
Deputy Department Head, Jiangsu CDC, China
2025-03-21
14:20-14:35
Global Vaccine Registration Strategy and Key Considerations
Speaker
Vaccine Innovation Forum World 2025
Howard Yuwen
SVP & CBO, SDM Bioservices, China
2025-03-21
14:35-15:00
SYN023 an Monoclonal Cocktail for Rabies Prophylaxis
Speaker
Vaccine Innovation Forum World 2025
Eric Tsao
CEO, Synermore Biologics , China
2025-03-21
15:00-15:30
茶歇
2025-03-21
15:30-15:45
Vaccine clinical development strategy in emerging market(s) and Commercial potentials
Speaker
Vaccine Innovation Forum World 2025
Adham Rezk
CEO, Celero Global, Singapore
2025-03-21
15:45-16:10
Enhancing Vaccine Equity through Global Partnerships and Local Manufacturing: Practices of Chinese Vaccine Manufacturers
Speaker
Vaccine Innovation Forum World 2025
Meng Li
Director of International Cooperation, Sinopharm CNBG
2025-03-21
16:10-16:35
The RIGHT Foundation: Mobilizing Partnerships for Equitable Vaccine Access
Speaker
Vaccine Innovation Forum World 2025
Hani Kim
Executive Director, The RIGHT Foundation, South Korea
2025-03-21
16:35-17:00
Chasing the miracles of science through strengthening external partnerships and development of ecosystems
Speaker
Vaccine Innovation Forum World 2025
Sean Du
Senior Director, External R&D, Sanofi Global R&D Vaccines
2025-03-22
09:00 -12:00
Track B: Immunobiology
2025-03-22
09:00-09:30
Innate Immunity and Vaccine Adjuvant Innovation: Leveraging the Body's First Line of Defense
Speaker
Vaccine Innovation Forum World 2025
Diana Boraschi
Distinguished Professor, Shenzhen Institute of Advanced Technology, China
2025-03-22
09:25-10:05
Vaccine adjuvants, mRNA mode of action, innate/trained immunity for vaccines

-Adjuvants induce innate immune responses that correlate with adaptive responses

-There is increasing evidence that some of these innate responses are accompanied by chromatin changes in monocytes, giving rise to the phenomenon of trained immunity

-Deciphering the molecular pathways and signalling targets can inform rational design of novel adjuvants, including those that can be combined with mRNA/LNP formulations

-Connecting in-depth understanding of adjuvant immunity can inform design choices and research directions for mRNA 2.0


Speaker
Vaccine Innovation Forum World 2025
Robbert van der Most
Former VP, Translational Science, BioNTech/ CEO, VaxxCellence
2025-03-22
10:05-10:30
TBC
Speaker
Vaccine Innovation Forum World 2025
Yunlong Cao
Yunlong Cao, Peking University
2025-03-22
11:00-11:25
Immunogenicity testing of pan-variant influenza and coronavirus vaccines using pseudotype platform technologies

1.     Background of pseudotype technologies

2.     Building pseudotype platforms

3.     Immunogenicity readouts for broadly-reactive vaccines

4.     Novel directions of pseudotype technology


Speaker
Vaccine Innovation Forum World 2025
Nigel Temperton
Professor, Director, Viral Pseudotype Unit, University of Kent, UK
2025-03-22
11:25-11:40
Bioassay for vaccine efficacy
Speaker
Vaccine Innovation Forum World 2025
Emanuele Montomoli
Co-founder& CSO, VisMederi, Italy
2025-03-22
11:40-12:05
Antigenic sin drives B cell evolution: lessons learned from the COVID-19 pandemic

The COVID-19 pandemic led to an unprecedented event, all people woridwide were exposed for the first time to the same virus, SARS.CoV.2 Wuhan, creating a globally shared original antigenic sin (OAS). However, during the course of the COVID-19 pandemic several varianis emerged exposing the human immune system to numerous antigenically distinct spike (S) proteins, the main target neutralizing antibodies. This unceasing interplay between SARS-CoV-2 variants and the human immune system has led to a  continuous maturation of the B cell compartment rising questions on how the SARS-CoV-2 Wuhan OAS memory B cell response evolvedcontroemerging variants. To shed light on the impact of SARS-CoV-2 0AS on B cellimmunity we longitudinaly analyzed at single celIevel spanel of almost 1,000 neutralizing human monoclonal antibodies (nAbs) isolated from COVID-19 vaccinees or people with hybrid immunity. Our analysis revealed that the Wuhan OAS,drove convergent maturation and expansion germlines(GHV3.53/3-66) which were restor to neutralize SARS-CoV-2 Omicron variants. In addition, we observed that after breakthrough infection with the antigenical distant Wuhan Omicron, people expanded new B cell germlines not derived by the Wuhan OAS to tackle SARS-CoV-2 variates. In spite of B cell maturaion,the uN.1 Omicron varianls, by introducing a single substitution in the S proteln (L455S) compared to its initial subineage, evaded the recently restored lGHV3-53/3-66 germlines. Our work decoded the cryptic role of OAS in COVID-19 and highlights the unceasing interplay between SARS-CoV.2 and the human immune system which may be a never-ending game for the next decades.

Speaker
Vaccine Innovation Forum World 2025
Emanuele Andreano
Project Leader, Fondazione Toscana Life Sciences, Italy
2025-03-22
12:30-13:30
午餐
2025-03-22
09:00 -12:00
Track A: Animal Vaccine
2025-03-22
09:00-09:25
Advancing One Health: Integrating Veterinary and Human Vaccines to Tackle Global Health Challenges
Speaker
Vaccine Innovation Forum World 2025
Alejandra Capozzo
Professor, Center Director, Universidad Abierta Interamericana (UAI), Argentina
2025-03-22
09:25-09:50
Trying to hit a moving target: New approaches to porcine reproductive and respiratory syndrome virus vaccine development

Porcine reproductive and respiratory syndrome viruses (PRRSV) cause significant economic losses in the global pig industry. Live attenuated PRRSV vaccines (MLV) are widely used but are weakly immunogenic and provide limited protection. There is therefore a pressing need to develop more efficacious next generation vaccines. I shall present three examples of novel approaches we have or are pursuing: (i) evaluation of the induction of broadly protective cellular immunity; (ii) augmenting protection by engineering MLV to express immune checkpoint inhibitors; and (iii) the application of structural vaccinology to develop a vaccine capable of inducing broadly neutralising antibodies.


Speaker
Vaccine Innovation Forum World 2025
Simon Graham
Professor, The Pirbright Institute, UK
2025-03-22
09:50-10:15
Immunological Insights into Animal Disease Control: A Path Toward Enhanced Vaccine Efficacy (TBD)
Speaker
Vaccine Innovation Forum World 2025
Huichen Guo
Professor, Lanzhou Veterinary Research Institute, China
2025-03-22
10:15-10:35
Development and Application of innovative adjuvants in animal vaccines
Speaker
Vaccine Innovation Forum World 2025
Huapeng Feng
Associate Professor ,Zhejiang Sci-Tech University, China
2025-03-22
10:35-10:50
茶歇
2025-03-22
11:00-11:25
African swine fever virus antigen discovery
Speaker
Vaccine Innovation Forum World 2025
Christopher Netherton
Professor, The Pirbright Institute, UK
2025-03-22
11:25-11:45
Progress and prospect of animal vaccine research and development
Speaker
Vaccine Innovation Forum World 2025
Jie Li
Head of R&D, Jinyu Baoling Biological Pharmaceutical, China
2025-03-22
11:45-12:05
Progress on the ASF DNA vaccine development in Philippines
Speaker
Vaccine Innovation Forum World 2025
Frank Chang
CSO, Reber Genetics, China
2025-03-22
12:05-12:25
The development of PDCoV and PEDV mRNA vaccines
Speaker
Vaccine Innovation Forum World 2025
Zhong Chen
Vice President, Suzhou HealiRNA Biotechnology
2025-03-22
12:30-13:30
午餐
Opening Remark
Vaccine Innovation Forum World 2025
Bin Wang
Founder, Advacccine, China

Dr. Bin Wang is the Co-founder, Chairman of Advaccine Biotechnology Co LTD. He is also holding a distinguished professor position at the Fudan University School of Basic Medical Sciences and serves as the chairman for the Nucleic Acid Vaccines branch of the Chinese Vaccine Society. His research area is focused on the effects of therapeutic vaccination to activate T cells and the mechanism of immune regulations. He has developed novel adjuvants and recombinant vaccines, novel DNA vaccine delivery, and led to several developed vaccines being tested in human clinical trials. He received his Ph.D. from the Cincinnati Children's Hospital at the University of Cincinnati School of Medicine in 1990. He completed his postdoc training in virology and immunology at the Wistar Institute in 1992 in Philadelphia. He became an instructor and assistant professor at the University of Pennsylvania Medical School from 1993 to 1998. He was a professor and served as the Chairman of the Department of Microbiology and Immunology for six years at the College of Biological Sciences, China Agricultural University before he joined Fudan University. He was one of the very early DNA vaccine technology inventors in the 90’s and performed the first-in-human DNA vaccine trials in 1994-1996. He has been involved in several clinical trials of therapeutic vaccines against chronic HBV infections in recent years and invented a novel prophylactic RSV vaccine currently under clinical phase II testing. He has published over 160 peer-review articles and awarded 35 US and 30 Chinese patents. He serves as an editorial board member for several international journals and executive member in several professional societies.

Plenary Panel: Revolutionizing Global Health: The Future of Vaccine Technology and Innovation
Vaccine Innovation Forum World 2025
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK

Professor Adrian V. S. Hill FRS is the Director and Founder of the Jenner Institute, and Mital Professor of Vaccinology at Oxford University. He is a passionate believer in the power of molecular medicine to address many of the most egregious health care inequities globally. His group have been leaders in the development of adenoviral and other vaccines against infectious diseases and he has tested these in extensively in over eighty clinical trials in Africa and Europe. In partnership with the Serum Institute of India and AstraZeneca the Jenner Institute developed rapidly a ChAdOx1 vector-based SARS-CoV-2 vaccine which saved an estimated 6.2 million lives in 2021 alone.

His lab also designed a newly licensed high efficacy malaria vaccine, R21/Matrix-MTM, which has recently shown unprecedented high efficacy in a phase III trial in four African countries, again in partnership with the Serum Institute of India and also Novavax Inc. This vaccine promises to make a major impact on reducing the 500,000 childhood deaths from malaria each year. In 2021 he was elected a Fellow of the Royal Society and is a Knight Commander of the Order of the British Empire (KBE).



Vaccine Innovation Forum World 2025
George Fu Gao
Professor, Chinese Academy of Sciences

George Fu Gao has been a key leader in the public health field, making remarkable contributions to research and discovery through basic research, clinical evaluation and advocacy. He has made many remarkable contributions to the scientific field of control and prevention of emerging infectious diseases. He obtained his DPhil degree from Oxford University, UK and did his postdoc work in both Oxford University and Harvard University (with a brief stay in Calgary University). Gao worked in Beijing Agricultural University (1986-1991), Oxford University (2001-2006), Institute of Microbiology, Chinese Academy Sciences (2004-2008, Director-General). China CDC (Director-General, 2017-2022), National Science Foundation of China (Vice-President, 2018-2022). Gao is a member (academician) of Chinese Academy of Sciences (CAS), an international member of the U.S. National Academy of Sciences (NAS), a foreign member of the U.K. Royal Society (RS), a member of the German National Academy of Sciences Leopoldina, a fellow of African Academy of Sciences and a fellow of The World Academy of Sciences (TWAS).


Vaccine Innovation Forum World 2025
Dan Barouch
Professor, Harvard Medical School

Dr. Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, a member of the Ragon Institute of MGH, MIT, and Harvard, and part of the Bill & Melinda Gates Foundation Collaboration for AIDS Vaccine Discovery.  His laboratory focuses on studying the immunology and pathogenesis of viral infections and developing novel vaccine and treatment strategies.  His group has led the development of vaccine candidates for multiple pathogens of global significance, including HIV, Zika virus, tuberculosis, and most recently SARS-CoV-2.  His work contributed to the development of the Johnson & Johnson COVID-19 vaccine and the evaluation of multiple COVID-19 vaccines and monoclonal antibody therapeutics.  He was elected to the National Academy of Medicine in 2020 and received the King Faisal Prize in Medicine in 2023.

 


Vaccine Innovation Forum World 2025
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium

Dr. Berlanda Scorza is an accomplished pharmaceutical executive with a strong focus on translating scientific innovations into tangible patient benefits. He currently serves as Vice President of Global Health R&D Vaccines at GSK. Additionally, he is the Chairman of the Board and General Manager of the GSK Vaccines Institute for Global Health, as well as a member of the GSK Country Executive Board in Italy.

Before joining GSK in 2020, Dr. Berlanda Scorza held senior leadership roles at the Bill & Melinda Gates Foundation and PATH, where he led key programs focused on the development of seasonal and pandemic influenza vaccines.

Earlier in his career, Dr. Berlanda Scorza was a senior scientist at Chiron Corporation and Novartis Vaccines, where he contributed to the development of innovative vaccine technologies, including a replicon RNA vaccine, the cell-cultured influenza vaccine Flucelvax, and the bacterial vaccine platform GMMA. Dr. Berlanda Scorza earned his Ph.D. from the University of Milano-Bicocca and completed his post-doctoral research at Imperial College London.


Plenary Panel: Global Vaccine Equity: Overcoming Challenges in Distribution and Access
Vaccine Innovation Forum World 2025
Rajinder Suri
CEO, DCVMN International, India
Rajinder as CEO-DCVMN International is responsible for leadership, governance, strategic vision and overall operational excellence of DCVMN. Rajinder is appointed as member GAVI’s Vaccine Investment Strategy (VIS) Steering Committee 2024, a permanent member of CEPI’s Joint Coordination Group (JCG), 2023-24, member PAVMs Talent Development WS and Regional Vaccine Manufacturing Collaborative (RVMC). To meet an un-precedented challenge posed by COVID-19, Rajinder has been actively involved in all global strategic initiatives along with COVAX partners-WHO, GAVI, CEPI, UNICEF and several other international organizations including industry associations to ensure equitable and timely access to vaccines. He has been member of several advisory expert groups including COVAX Manufacturing & Supply Chain Task Force Leadership Team, G-20 Health Working Group and Market Design and Demand Intelligence pillar of PAVM. Rajinder has over 25 years of top management experience in the industry including at the Board of Directors of the Indian subsidiary of Sanofi Pasteur and as CEO-Panacea Biotec. He has served as Member-GAVI-PPC as well as Vice-President, DCVMN Executive Committee.
Vaccine Innovation Forum World 2025
Hun Kim
President of Global Business, SK Bioscience, South Korea

Dr. Hun Kim is the President of Global Business at SK Bioscience. His role is to oversee the company's product and platform portfolio in a comprehensive perspective from R&D to commercialization through global alliance and external innovation.

Dr. Hun Kim started his biopharmaceutical career in 1992 as a researcher at Green Cross Corporation, In 2000, he moved on to Berna Biotech, a part of Crucell at present. In 2008, he joined SK Chemicals,the parent company of SK Bioscience, and lead the company's expansion in vaccine R&D, Quality and manufacturing capabilities.

Under his oversight, the company developed and received approval for cell culture-based influenza vaccines (SKYCellflu/SKYCellflu Quadrivalent), varicella/herpes zoster vaccines (SKYVaricella/SKYZoster),and Pneumococcal Conjugation Vaccines. During the Pandemic, it successfully manufactured and supplied COVID-19 vaccines developed by AstraZeneca and NovaVax. With support from CEPI and BMGF, SK Bioscience also developed its own COVID-19 vaccine (SKYCovione), which became the first domestically developed COVID-19 vaccine to be approved in Korea.


Vaccine Innovation Forum World 2025
Jing Wang
Board Executive Director, Chief Commercial Officer, CanSino Biologics, China
Vaccine Innovation Forum World 2025
Raman Rao
CEO, Hilleman Laboratories

Dr. Raman Rao joined as the Chief Executive Officer at Hilleman Laboratories in February 2020. Dr. Rao has more than two decades of experience in research and development, manufacturing and commercialisation of vaccines for infectious diseases in global pharma and biotech companies. Prior to joining Hilleman Laboratories, Dr. Rao served as the Vice President of Global Product Operations with Takeda, Singapore, where he enhanced the global product portfolio while successfully leading an international team across Japan, Singapore and the United States. The teams worked in the areas of dengue, norovirus, zika, polio and other vaccines.

Dr. Rao started his career in 2002 with Shantha Biotechnics Limited, part of Sanofi Aventis Group in India, in Clinical Research and Scientific Affairs. He holds a MD in Medical Microbiology from the Postgraduate Institute of Medical Education and Research.

He plans to carry forward Dr. Maurice Hilleman’s legacy for providing effective solutions for global health, especially those impacting low- and middle-income countries.


茶歇

Keynote: Innovative Vaccine Platforms: Accelerating Global Health R&D
Vaccine Innovation Forum World 2025
Francesco Berlanda Scorza
VP R&D, Global Health R&D Vaccines Head and GVGH Institute, GSK, Belgium

Dr. Berlanda Scorza is an accomplished pharmaceutical executive with a strong focus on translating scientific innovations into tangible patient benefits. He currently serves as Vice President of Global Health R&D Vaccines at GSK. Additionally, he is the Chairman of the Board and General Manager of the GSK Vaccines Institute for Global Health, as well as a member of the GSK Country Executive Board in Italy.

Before joining GSK in 2020, Dr. Berlanda Scorza held senior leadership roles at the Bill & Melinda Gates Foundation and PATH, where he led key programs focused on the development of seasonal and pandemic influenza vaccines.

Earlier in his career, Dr. Berlanda Scorza was a senior scientist at Chiron Corporation and Novartis Vaccines, where he contributed to the development of innovative vaccine technologies, including a replicon RNA vaccine, the cell-cultured influenza vaccine Flucelvax, and the bacterial vaccine platform GMMA. Dr. Berlanda Scorza earned his Ph.D. from the University of Milano-Bicocca and completed his post-doctoral research at Imperial College London.


Correlates of Protection for Respiratory Virus Vaccines

Vaccine Innovation Forum World 2025
Dan Barouch
Professor, Harvard Medical School

Dr. Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, a member of the Ragon Institute of MGH, MIT, and Harvard, and part of the Bill & Melinda Gates Foundation Collaboration for AIDS Vaccine Discovery.  His laboratory focuses on studying the immunology and pathogenesis of viral infections and developing novel vaccine and treatment strategies.  His group has led the development of vaccine candidates for multiple pathogens of global significance, including HIV, Zika virus, tuberculosis, and most recently SARS-CoV-2.  His work contributed to the development of the Johnson & Johnson COVID-19 vaccine and the evaluation of multiple COVID-19 vaccines and monoclonal antibody therapeutics.  He was elected to the National Academy of Medicine in 2020 and received the King Faisal Prize in Medicine in 2023.

 


午餐
Pan-sarbeCoV vaccine: a dream or reality?
Vaccine Innovation Forum World 2025
Linfa Wang
Professor, Duke-NUS Medical School, Singapore

Dr. Linfa Wang is a professor of the Programme in Emerging Infectious Diseases at Duke-NUS Medical School, and the inaugural executive director of PREPARE, Ministry of Health, Singapore. He is an international leader in the field of emerging zoonotic viruses and virus-host interaction. In response to the COVID-19 pandemic, he has served and is serving on multiple WHO committees for COVID-19, including the WHO IHR Emergency Committee. Prof. Wang has more than 500 scientific publications. He was the Editor-in-Chief for the Virology Journal from 2112-2022. Prof. Wang was elected to the Australian Academy of Technological Sciences and Engineering in 2010, the American Academy of Microbiology in 2021 and the Australian Academy of Sciences in 2023. He received the Singapore President Science Award in 2021

mRNA Vaccines in Low- and Middle-Income Countries: Bridging the Gap
Vaccine Innovation Forum World 2025
Kiat Ruxrungtham
Director of Chula Vaccine Research Center, Chulalongkorn University
Kiat Ruxrungtham, is a Professor of Medicine, Department of Medicine , Faculty of Medicine, Chulalongkorn University; and Scientific Chair of the Chula Vaccine Research Center (ChulaVRC); and Director of the Covid19 Vaccine Development Program, ChulaVRC. He is providing teaching and patient care on Allergy -Clinical Immunology and HIV Medicine at the King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University; and is mentoring junior researchers on HIV medicine at HIVNAT, TRCARC; vaccine and Immunology (at Chula Vaccine Research Center); and also on clinical trials. He is currently leading the Chula-Covid19 mRNA vaccine development program at ChulaVRC. Honors: He has received several awards: 2006 Outstanding Internist Award on Medical Academy, Royal College of Physicians, Thailand 2007 Outstanding Researcher Award, and the Highest Citation Award, Chulalongkorn University, Bangkok, Thailand 2011 Senior Research Scholar Award, the Thailand Research Fund 2011 Outstanding Researcher Award, National Research Council, Thailand 2015 Senior Research Scholar Award, the Thailand Research Fund 2015 Outstanding Research Award, the Thailand Research Fund 2022 A Royal Award “Contributors to the development of the country’s vaccines” from Her Royal Highness Princess Maha Chakri Sirindhorn at the 10th Vaccination Conference Publications: He has published more than 370 peer review papers on HIV, immunology, allergy, and vaccine. Contributions to national and international academics and professional organization: 1. Former President of the Allergy, Asthma and Immunology Association, Thailand (AAIAT) 2. Former President of the Thai AIDS Society (TAS) 3. Co-chair of the Co-chair of the APAACI and APAAAPARI 2018, Bangkok, Thailand 4. Co-chair of the World Allergy Congress 2023, Bangkok, Thailand 5. Chief-editor, Asian Pacific Journal of Allergy and Immunology (APJAI)
Impact of glycosylation on a broad-spectrum vaccine against influenza
Vaccine Innovation Forum World 2025
JR Chen
COO,RuenHuei biopharma, China

Dr. Chen is a prominent scientist specializing in human vaccine research and antiviral therapies. He currently serves as the Chief Operating Officer at RuenHuei Biopharmaceuticals Inc., where he oversees the development and production of new vaccine candidates. Dr. Chen joined RH Biopharma in August 2018, bringing over a decade of practical industry experience in vaccine development. Before his role at RH Biopharma, Dr. Chen held several key positions at Adimmune Corporation, including the Director and Manager of the R&D Department. At Adimmune, he was instrumental in developing the EV71 vaccine and advancing a cell culture-based production process for influenza vaccines. Dr. Chen's academic background includes a Ph.D. from National Yang-Ming University in Taipei, Taiwan, where he specialized in Biochemistry and Molecular Biology. He also completed postdoctoral fellowships at the Genomics Research Center, Academia Sinica, and the Vollum Institute at Oregon Health and Science University in the United States. His research has significantly contributed to the field of vaccine development, particularly in creating more effective influenza vaccines and understanding the immune responses to viral infections. He is currently also special technical expert at the Department of Pharmacy at National Taiwan University and an associate professor at the Department of Chemistry at National Chung Hsing University

A New Strategy for Vaccine Immune Evaluation System
Vaccine Innovation Forum World 2025
Chongyang Liang
Prof., Jilin University;Scientific Advisor, ProMab Forethought;

Professor Liang is dedicated to the development of large molecular drugs in the field of recombinant protein. He has been engaged in the research of drug action mechanism-related structural biology and physicochemical analysis for many years, leading the development of multiple innovative monoclonal antibody drugs and subunit vaccines. Through the transformation of achievements and cooperation with enterprises, he has promoted the approval of clinical trials or market launch by the US FDA and China NMPA.

Reserved by Joinn Lab

茶歇

Decoding Antibody Response to MERS-CoV in Wild Dromedary Camels
Vaccine Innovation Forum World 2025
Linqi Zhang
Professor, Tsinghua University
Professor Linqi Zhang is the Director of the Comprehensive AIDS Research Center at Tsinghua University. Prof. Zhang's research focuses on HIV-1 pathogenesis and vaccine development, and has recently expanded to the field of emerging and re-emerging human viral pathogens such as SARS-CoV-1/2 and MERS-CoV. Using cutting-edge antibody and combinatorial antigen library techniques, Prof. Zhang’s research aims to characterize protective antibody immunity in infected humans and rational design of effective vaccines and therapies against the viral infection. Professor Zhang is the recipient of the National Outstanding Young Scientist Award, privileged Changjiang Professorship, and Bayer and Vanke Chair professor. He has published extensively and is among the most cited Chinese researchers in the field of microbiology and immunology. Professor Zhang has also served as a member of national expert and advisory board to the Chinese government and several international organizations on HIV/AIDS and infectious diseases,and was recently elected as a Foreign Fellow of the African Academy of Sciences.
Vaccine Clinical Trials: Practical Insights to Avoid Pitfalls
Vaccine Innovation Forum World 2025
Zhaojun Mo
GM, Vaccine Clinical BU at SDM Bioservices / Shanghai SDM, China

-17+ Years in Vaccine Clinical Development 

-Former Director, Guangxi CDC Vaccine Clinical Research Institute (2010-2022), managing nearly 300 clinical trials and serving as PI for 70+ vaccine trials, including large-scale, multi-center efficacy studies. 

-CDE and national vaccine task force expert, contributing to national vaccine trial regulations, guidelines, and major drug innovation projects. 

-Led groundbreaking trials: world’s first EV71 inactivated vaccine, China’s first mRNA COVID-19 vaccine, HPV, rotavirus, rabies, IPV, bOPV, influenza, pneumococcal, and meningococcal vaccines. 

-Published 30+ SCI; editor for Vaccinology (7th Edition) and Preventive Vaccine Clinical Trial Design and Implementation. 

-Former roles in national industry committees: NMPA Drug Review Committee, State Council Vaccine R&D Task Force, National Immunization Program, and GCP inspector.

Clinical development for RSV vaccine in China
Vaccine Innovation Forum World 2025
Wei Tan
SVP, Head of China Research and External Collaboration, Clover Biopharmaceutical, China

Dr. Tan is responsible for drug discovery, preclinical development, translation research and external collaboration in China. Dr. Tan got his Ph.D. in Molecular Medicine from UT Health Science Center San Antonio and received his Postdoctoral training with Dr. Michael Karin at UC San Diego. Dr. Tan worked in Pfizer and Novartis for 9 years, specialized in drug discovery and translational research, bridging preclinical research to early clinical trials. Dr. Tan worked at Biosion Biotech and Coherent Biopharma before he joined Clover. Dr. Tan was selected as Jiangsu Innovation and Entrepreneur Talent and Suzhou Innovation and Entrepreneur Leading Talent.

Pan-β-coronavirus vaccine development
Vaccine Innovation Forum World 2025
Shibo Jiang
Professor, Fudan University, China
Dr. Shibo Jiang is a Professor at the Shanghai Institute of Infectious Disease and Biosecurity of Fudan University, Shanghai, China. His main research interest is the development of antiviral drugs and vaccines. He has published 572 papers (total IF: 7,662, average IF: 13.4) in SCI journals such as Cell (x3), Nature (x2), Science (x2), Lancet (x4), CNS’ sister journals (x71), with total 45,327 citations and an h-index of 105. He has applied for 104 patents, 54 of which were issued, and 11 of them were licensed out with 3 classes of innovative drugs and medical products used in clinics.

Poster Session

Cocktail Party (Invited Only)

Immunotherapy for Cancer
Vaccine Innovation Forum World 2025
David Weiner
Executive Vice President, The Wistar Institute, USA

Dr. David Weiner directs a translational research laboratory at The Wistar Institute in the area of Molecular Immunology. His group is one of the pioneering research teams in establishing the field of DNA vaccines and immunotherapies. Important reports from his lab include the first DNA vaccine studied for HIV as well as for cancer immunotherapy, the early development of DNA encoded genetic adjuvants including the particularly relevant IL-12, advances in gene optimization, and advances in electroporation (EP) technologies resulting in improved gene delivery among others. His group worked with collaborators to become the first to move DNA technology into human study. His laboratory’s work helped revitalize the field through advancement of new synthetic DNA design and modification of EP delivery approaches resulting in potent immune induction as well as the first successful Phase IIb DNA efficacy study (for HPV immunotherapy) in humans. Dr. Weiner is the recipient of numerous honors including election as a fellow to both the American Association for the Advancement of Science in 2011 and the International Society for Vaccines in 2012. He is the recipient of the NIH Director’s Transformative Research Award and received the Vaccine Industry Excellence Award for Best Academic Research Team in 2015 at the World Vaccine Congress. Weiner was honored with the prestigious Hilleman Lectureship in 2015 at the Children’s Hospital of Philadelphia Grand Rounds session and received a Stone Family Award from Abramson Cancer Center for his groundbreaking work on DNA vaccines for cancer immunotherapy. In 2019, Dr. Weiner was honored with the Scientific Achievement Award from Life Sciences PA (LSPA). Dr. Weiner returned to Wistar in 2016 from his position at The University of Pennsylvania School of Medicine as professor of Pathology and Laboratory Medicine. From 1990 to 1993, Weiner held a joint position as assistant professor of Pathology and Laboratory Medicine at The Wistar Institute and the University of Pennsylvania School of Medicine. Dr. Weiner is a co-founder of Inovio Pharmaceuticals and is a member of the Board of Directors. Dr. Weiner graduated with a B.S. in biology from SUNY at Stony Brook, N.Y., a M.S. in biology from the University of Cincinnati and a Ph.D. in developmental biology from the University of Cincinnati College of Medicine.

Development of mRNA vaccines: from infectious diseases to oncology
Vaccine Innovation Forum World 2025
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany

Ruben Rizzi, physician by training, SVP of Global Regulatory Affairs at BioNTech. I joined the company in December 2019 just before the pandemic, and I have been the global regulatory lead for BioNTech for our COVID-19 development. Currently, I am still supporting the lifecycle of our COVID-19 vaccine, and I am co-leading the Global Regulatory Affairs department at BioNTech and working closely with the teams that are responsible for the development of BioNTech´s pipeline, post-approval activities and labelling


Expanding the Frontier: mRNA Vaccines for Cancer and Autoimmune Diseases(TBD)
Vaccine Innovation Forum World 2025
Bo Ying
Founder, CEO, Abogen

Dr. Bo Ying has dedicated over a decade of his career to the technology research into nucleic acid -based therapeutics and the development of transformative drugs. He founded Abogen, a biotechnology company with a mission of curing otherwise untreatable diseases through mRNA science and technology. 


As the founder, Dr Ying also has served as Chairman of the board and CEO of Abogen. Under his leadership, the company has established its own proprietary mRNA platform and delivery technology that allowed the development of the therapeutics and vaccines for infectious diseases, cancer, and rare diseases. Most recently, Abogen’s mRNA platform capabilities have come together to allow the authorized use and approval of first China made mRNA vaccine against the COVID-19 pandemic. 


Prior to founding Abogen, Dr Ying had held several roles at numerous leading biopharmaceutical and biotechnologies companies in the US, mainly responsible for leading drug formulation, process development, technology transfer and manufacturing. Across his career, he takes pride in a broad array of innovative drug developing experiences in siRNA, mRNA-based therapies for tumor immunotherapy、cancer vaccines and gene-editing drug product candidates. 

Dr. Ying received his bachelor’s degree in life sciences from Fudan University, Shanghai, and Ph.D. in pharmaceutical sciences from Northeastern University. He is credited as the inventor of a dozen issued patents and patent applications, and his work appears in journals such as Cell and Lancet. 


Over the years, Dr. Ying has held several positions in influential organizations. From 2018 to 2019, he served as the president of the Chinese-American BioMedical Association (CABA) in Boston, where he made contributions to the advancement of science and technological innovation with great potential to improve human health.


SynNeogen: unleash the power of immune system
Vaccine Innovation Forum World 2025
Hanxin Lu
Vice President of R&D at Chimigen Biomedical

Dr. Lu earned his Ph.D. in Genetics from George Washington University.

With 16 years of pioneering experience in biomedical product development, Dr. Lu has led multidisciplinary teams in advancing both therapeutic and prophylactic vaccine platforms. His groundbreaking work encompasses immunotherapy vaccines targeting metabolic disorders (e.g., hypercholesterolemia) and neurodegenerative pathologies, as well as next-generation vaccines against emerging infectious diseases such as respiratory syncytial virus (RSV), pandemic influenza, and Ebola.

Dr. Lu's scientific leadership encompasses the full spectrum of vaccine development, from target validation and rational design to adjuvant development, preclinical modeling (animal studies and pharmacodynamics), biomarker-guided clinical trials (Phases I-III), and regulatory-aligned virological and safety/efficacy evaluations.


Precision treatment of pancreatic cancer - personalized tumor treatment vaccine
Vaccine Innovation Forum World 2025
Landian Hu
CEO, Anda Biology Medicine Development (Shenzhen) , China

Doctor Hu is the founder, chairman and full-time CEO of Anda Biology. She was a former researcher of the Chinese Academy of Sciences Shanghai Institute of Nutrition and Health, visiting scholar of the Max-Planck-Institute for Molecular Genetics in Germany, and visiting scholar of the Cambridge Molecular Biology Laboratory in the UK. She independently undertook key projects of the National Natural Science Foundation of China and 863 projects as the project leader, participated in the Super 973 projects, the Chinese Academy of Sciences' Leading Special Research on Stem Cell and Regenerative Medicine, and the National Twelfth Five Year Plan Major Special Projects. Expert in the Second Review of Outstanding Youth Fund, Outstanding Youth Fund, and Key Projects of the National Natural Science Foundation of China, and expert in risk assessment of the Ministry of Science and Technology in 2013.

She has been engaged in molecular genetics research of diseases for a long time and has established a series of genetic analysis techniques that can be applied to stem cell clinical transformation research such as stem cell quality control, in vivo genetic tracing, stem cell maintenance, and cell phenotype transformation, laying the foundation for stem cell based disease diagnosis and treatment. Dr Hu has published more than 70 SCI papers and won the first prize for scientific and technological progress in Shanghai (second place completion).

 

She has participated as the leader of the innovation team in 2018 in the first Shenzhen Women's Innovation and Entrepreneurship Competition. After winning the award, she founded Anda Biology Medicine Development (Shenzhen) Co., Ltd and she is serving as its full-time CEO. In the past four years, she has led the company's employees to develop personalized immunotherapy vaccine for pancreatic cancer, universal cancer vaccines, cell therapy and other products. Among which, PCNAT-1, a therapeutic personalized vaccine for pancreatic cancer, has won the FDA orphan drug qualification certification.


茶歇
Induction of tertiary lymphatic structures (TLS) by a novel immunotherapeutic strategy against solid tumors
Vaccine Innovation Forum World 2025
Bin Wang
Founder, Advacccine, China

Dr. Bin Wang is the Co-founder, Chairman of Advaccine Biotechnology Co LTD. He is also holding a distinguished professor position at the Fudan University School of Basic Medical Sciences and serves as the chairman for the Nucleic Acid Vaccines branch of the Chinese Vaccine Society. His research area is focused on the effects of therapeutic vaccination to activate T cells and the mechanism of immune regulations. He has developed novel adjuvants and recombinant vaccines, novel DNA vaccine delivery, and led to several developed vaccines being tested in human clinical trials. He received his Ph.D. from the Cincinnati Children's Hospital at the University of Cincinnati School of Medicine in 1990. He completed his postdoc training in virology and immunology at the Wistar Institute in 1992 in Philadelphia. He became an instructor and assistant professor at the University of Pennsylvania Medical School from 1993 to 1998. He was a professor and served as the Chairman of the Department of Microbiology and Immunology for six years at the College of Biological Sciences, China Agricultural University before he joined Fudan University. He was one of the very early DNA vaccine technology inventors in the 90’s and performed the first-in-human DNA vaccine trials in 1994-1996. He has been involved in several clinical trials of therapeutic vaccines against chronic HBV infections in recent years and invented a novel prophylactic RSV vaccine currently under clinical phase II testing. He has published over 160 peer-review articles and awarded 35 US and 30 Chinese patents. He serves as an editorial board member for several international journals and executive member in several professional societies.

Innovative Design of mRNA Sequences and Delivery Systems for Therapeutic Cancer Vaccines
Vaccine Innovation Forum World 2025
Xiangrong Song
Co-Founder, Westgene
Xiangrong Song is a full professor at Sichuan University and a pharmaceutical scientist at National Key Laboratory of Biotherapy. The Song lab has developed the targeted delivery systems for gene drugs and small molecules to treat tumors, atherosclerosis, ocular diseases, infection or brain diseases. Two novel drug candidates (IND) have been approved for phase I clinical trials. She has authored more than 100 papers and is an inventor of more than 50 issued / pending patents worldwide. The technologies that Dr. Song and her colleagues have developed formed the basis for the launch of 2 biotechnology companies. The two companies are translating the aforementioned academic innovations toward commercialization and societal impact. In 2019, she was a recipient of the first prize of Science and Technology Award in Chinese National Medicine Association, for the research on immune function of Yi nationality's medicine. In 2022, she was named as the elite of science and technology in China.
A therapeutic cancer vaccine platform enhancing cross-presentation and CD8+ CTL response through targeting dendritic cell cytosol
Vaccine Innovation Forum World 2025
Joon Haeng Rhee
Professor, Chonnam National University Medical School, South Korea
Dr. Joon Haeng Rhee is a graduate of Chonnam National University Medical School and received PhD from the same university. He has been working on molecular microbial pathogenesis and vaccine biology for more than 30 years. His team was the first reporter of the whole genome sequence of V. vulnificus, which became one of the most widely used standard strains in the Vibrio research field. Vaccine study was first started aiming the high mortality V. vulnificus infections. During the vaccine research, his team came across the finding that a flagellin protein of V. vulnificus has an excellent mucosal adjuvant activity in late 1990s. Now flagellin is applied to the development of effective vaccines and immunotherapeutics against diverse diseases such as cancers, allergies, and Alzheimer’s disease. He served the president of Korean Vaccine Society (KVS) from 2013 to 2015. He was elected as an ISV Fellow and serves a member of ISV Executive Board. He is currently the director of Clinical Vaccine R&D Center and Combinatorial Tumor Immunotherapy Research Center of Chonnam National University. As of November 2023, he has more than 170 papers published in peer-reviewed journals and named as an inventor on 40 patents.
Strengthening Vaccine Manufacturing Capacity in Developing Countries: The Role of DCVMN
Vaccine Innovation Forum World 2025
Rajinder Suri
CEO, DCVMN International, India
Rajinder as CEO-DCVMN International is responsible for leadership, governance, strategic vision and overall operational excellence of DCVMN. Rajinder is appointed as member GAVI’s Vaccine Investment Strategy (VIS) Steering Committee 2024, a permanent member of CEPI’s Joint Coordination Group (JCG), 2023-24, member PAVMs Talent Development WS and Regional Vaccine Manufacturing Collaborative (RVMC). To meet an un-precedented challenge posed by COVID-19, Rajinder has been actively involved in all global strategic initiatives along with COVAX partners-WHO, GAVI, CEPI, UNICEF and several other international organizations including industry associations to ensure equitable and timely access to vaccines. He has been member of several advisory expert groups including COVAX Manufacturing & Supply Chain Task Force Leadership Team, G-20 Health Working Group and Market Design and Demand Intelligence pillar of PAVM. Rajinder has over 25 years of top management experience in the industry including at the Board of Directors of the Indian subsidiary of Sanofi Pasteur and as CEO-Panacea Biotec. He has served as Member-GAVI-PPC as well as Vice-President, DCVMN Executive Committee.
Innovative products for low resource settings
Vaccine Innovation Forum World 2025
Melanie Saville
CSO, PATH, USA

Melanie Saville, MBBS, is PATH’s Chief Scientific Officer. She leads PATH’s product development division, which includes a global team dedicated to the development, introduction, and scale of vaccines, medical devices, and diagnostics.

Dr. Saville is a distinguished physician specializing in virology with more than two decades of experience developing and licensing vaccines for global use. Her contributions over the past 20 years have included the development of vaccines for seasonal and pandemic influenza, as well as pediatric combinations and vaccines against rabies, Japanese encephalitis, dengue, Ebola, and SARS-CoV-2.

Before joining PATH, Dr. Saville worked with the Coalition for Epidemic Preparedness Innovations (CEPI), where she served as the Executive Director of Vaccine Research and Development, leading technical teams supporting vaccine development. She also served as the R&D and manufacturing workstream leader for COVAX, part of a global collaboration to speed development, production, and equitable access to COVID-19 tests, treatments, and vaccines.

Dr. Saville holds a medical degree, a master’s degree in medical virology, and a Bachelor of Science in molecular biology from University College, London.


China Vaccine Industry Overview
Vaccine Innovation Forum World 2025
Yuan Yuan
Country Representative, PATH China

Ms. Yuan Yuan is country representative in the PATH China representative office in Shanghai. She manages the relationships with partners in China and oversees management and business development for PATH China office. Ms. Yuan joined PATH in January 2007 and has been in multiple roles including Finance & Administration Officer, Project Manager and Alliance Manager. In her 18 years at PATH, her projects include Japanese Encephalitis vaccine WHO prequalification, Rotavirus vaccine development, Pneumococcal conjugate vaccine development, Oral Polio Vaccine international clinical trial, Sabin IPV D antigen international standardization and HPV vaccine prequalification. She is familiar with the life cycle of vaccines including manufacturing, quality, clinical, regulatory, pharmacovigilance, biosafety and biosecurity. In January 2023, Ms. Yuan was elected as the Secretary General of the Council for the Promotion of International Vaccine Cooperation (CPIVC) under the Chinese Association for Vaccines (CAV). Prior to joining PATH, she worked as a project manager with Integrity Metals in Singapore and Indonesia. Ms. Yuan obtained her B.A., MBA, and MPH from Peking University.


BioKangtai’s Strategy and Technology Transfer Practices in the Era of Global Vaccine Cooperation
Vaccine Innovation Forum World 2025
Qian Zhang
Director General, International BU, Kangtai Bio

Zhang Qian, Director General of International BU of Shenzhen Kangtai Biological Products Co., Ltd.,, member of Council for the Promotion of International Vaccine Cooperation, graduated from School of Economics & Management, Tongji University and ESSEC business school. She is in charge of international business development, regulatory affairs and cooperation. Several core vaccine manufacturing technologies including human diploid cell rabies vaccine and inactivated polio vaccine etc have been successfully introduced by her. In addition, she leads the international registration and export and expand the business in multiple emerging market countries, and has exported finished products and intermediate products to Southeast Asia and South Asia and Middle East countries. Finished product registration, bulk export and technology transfer in Southeast Asia, Middle East, Latin America, CIS and Africa etc is being implemented. She is also responsible for communication and cooperation with embassies and consulates in China, multinational companies, international research institutes and organizations.

茶歇
Development of the vaccine production facility and tech transfer in Latin America
Vaccine Innovation Forum World 2025
Adel Sattarova
Head of Project Management Department, FSUE SPbSRIVS FMBA of Russia

Ms Adel Sattarova holds Specialist Degree in Pharmacy. She has been working at the Saint Petersburg Scientific Research Institute of Vaccines and Serums (FSUE SPbSRIVS FMBA of Russia) since 2016 and currently holds a Head of Project Management Department position. Ms Adel Sattarova has an experience in regulatory affairs, leads the projects, one of which is the WHO prequalification of the influenza vaccine FLU-M® – the product developed and produced by FSUE SPbSRIVS FMBA of Russia with a production site in Saint Petersburg, Russia and Managua, Nicaragua.


Future prospects for vaccine R&d and manufacturing
Vaccine Innovation Forum World 2025
Hun Kim
President of Global Business, SK Bioscience, South Korea

Dr. Hun Kim is the President of Global Business at SK Bioscience. His role is to oversee the company's product and platform portfolio in a comprehensive perspective from R&D to commercialization through global alliance and external innovation.

Dr. Hun Kim started his biopharmaceutical career in 1992 as a researcher at Green Cross Corporation, In 2000, he moved on to Berna Biotech, a part of Crucell at present. In 2008, he joined SK Chemicals,the parent company of SK Bioscience, and lead the company's expansion in vaccine R&D, Quality and manufacturing capabilities.

Under his oversight, the company developed and received approval for cell culture-based influenza vaccines (SKYCellflu/SKYCellflu Quadrivalent), varicella/herpes zoster vaccines (SKYVaricella/SKYZoster),and Pneumococcal Conjugation Vaccines. During the Pandemic, it successfully manufactured and supplied COVID-19 vaccines developed by AstraZeneca and NovaVax. With support from CEPI and BMGF, SK Bioscience also developed its own COVID-19 vaccine (SKYCovione), which became the first domestically developed COVID-19 vaccine to be approved in Korea.


Overview of HPV vaccine development and global vaccine introduction status
Vaccine Innovation Forum World 2025
Peter Dull
Deputy Director, Gates Foundation, USA

Peter Dull is the deputy director for Integrated Clinical Vaccine Development within the Global Health Division. In this role, he provides technical and strategic guidance on clinical development to the foundation’s program strategy teams, including Pneumonia and Enteric and Diarrheal Diseases, and external partners. In addition, he leads the foundation’s vaccine development activities for HPV vaccines, including efforts with reduced dose schedules.

Peter joined the foundation in 2014 after 10 years at Novartis Vaccines and Diagnostics where he was the clinical franchise head for Meningitis and Sepsis Vaccines. During that time, he led the clinical development and global licensure for a quadrivalent meningococcal glycoconjugate vaccine (Menveo; MenACWY-CRM) as well as a protein-based serogroup B meningococcal vaccine (Bexsero; 4CMenB). His work also included early clinical development of Group B strep glycoconjugate and Staph aureus vaccines. Prior to joining Novartis, he was an epidemic intelligence service officer in the Meningitis and Special Pathogens Branch at the U.S. Centers for Disease Control and completed subspecialty training in infectious diseases at Emory University.

He received his medical degree at University of Wisconsin-Madison and Internal Medicine training at Oregon Health Sciences University.


Systemic and mucosal immunity: separate roles and cooperation
Vaccine Innovation Forum World 2025
Rita Carsetti
VP, IUIS; Prof, Bambino Gesù Children Hospital, Italy

Rita Carsetti trained in Medicine and Obstetrics and Gynecology at La Sapienza University of Rome (Italy) before discovering her passion for science during her postdoctoral training in the United States, at the M.D. Anderson Hospital in Houston (Texas). She followed this with a second postdoc at the Max-Plank Institute for Immunobiology in Freiburg (Germany), in the department of Georges Koehler, who had received the Nobel Prize for the discovery of monoclonal antibodies. At the Max-Planck she also became responsible for the flow cytometry core facility and later worked in the departments of Michael Reth and Thomas Boehm. After 13 years in Germany, she returned to Italy (Bambino Gesù Children’s Hospital, Rome) with a strong background in basic immunology of murine B cells. At this point she turned her attention to human B cells for a more patient-orientated research approach. The close contact with clinicians and her role as head of the Diagnostic Immunology Unit gave her the possibility to learn how human B cells change with age, immunodeficiency, infection, transplantation, and vaccination. The COVID-19 pandemic and the global vaccination campaign gave her the possibility to learn more about the development, function, and persistence of human memory B cells after vaccination in healthy subjects and patients with primary or secondary immunodeficiencies. Throughout her career, Rita Carsetti has made a number of discoveries regarding the development of human and murine B cell populations and the effect changes in such populations have on infection and immunodeficiencies in humans. Her recent work on SARS-CoV-2 and RNA vaccination has been vital in demonstrating how human memory B cells aid immune protection and how mucosal immunity is induced in neonates born to SARS-CoV-2 infected mothers. Altogether, Rita Carsetti’s work is extremely relevant to both basic and clinical immunologists.

Inhaled Adenovirus (Human type 5) Vectored Tuberculosis Vaccine
Vaccine Innovation Forum World 2025
Fang Xu
Sr. Scientist, CanSinoBIO, China

Ph.D. in Molecular Virology from Wageningen University, the Netherlands. Formerly served as a researcher at the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) in Canada, the Australian National University, and the University of Amsterdam, focusing on the molecular pathogenesis of influenza virus, respiratory syncytial virus, and baculovirus, as well as vaccine development for respiratory diseases. Currently employed at CanSino Biologics Inc. as a Senior Scientist in the R&D Center. Leading and driving major R&D projects and international collaborations within the company. As a project leader, working on the development of an inhaled adenovirus-vectored tuberculosis vaccine and dedicated to advancing mucosal vaccines and novel vaccine delivery technologies.

The nose knows why and how
Vaccine Innovation Forum World 2025
Huimin Yan
Professor, Fudan University

Dr. Yan graduated and earned his B.S. and Ph.D at Wuhan University. He continued to work as a teaching staff member in College of Life Sciences, Wuhan University until 1998. From 1998 to 2002, he worked with Prof. Michael E. Lamm as a Research Associate in Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio and conducted scientific research on mucosal immune functions of IgA in relation to virus infections. He returned to Wuhan University in autumn 2002 and joined in the newly established Modern Virology Research Center, College of Life Sciences, Wuhan University as an associate professor. In 2006, he moved to the Wuhan Institute of Virology, Chinese Academy of Sciences, where he was appointed as a professor and group leader to set up an independent research lab named Mucosal Immunity Research Group. His lab is a group member of the State Key Laboratory of Virology in China. He has continued his research on the mucosal IgA functions against virus infections and focused more on the intra-epithelial activities of IgA against viral non-surface and non-structure components, which helps to reveal novel anti-viral mechanisms of IgA antibodies. His lab demonstrated that measles virus (MV) non-surface protein such as matrix protein (M), non-structural protein such as phosphoprotein (P) specific IgA can interact with viral newly synthesized proteins during IgA transport through the viral infected epithelial cells, and inhibit viral replication intracellularly. He also extended his study in developing optimized recombinant flagellin as mucosal adjuvant for designing novel subunit mucosal vaccines. He obtains 3 patents issued by the United States Patent and Trademark Office and 4 patents issued by the State Intellectual Property Office of the PRC related to novel flagellin adjuvants as well as anti-caries vaccine and anti-RSV vaccine. His research is mostly funded by National Natural Science Foundation of China, the Ministry of Science and Technology of China.

A sequential Intranasal Protein Vaccine Triggers Class Switching from Intramuscularly Primed IgG to Mucosal IgA against SARS-CoV-2
Vaccine Innovation Forum World 2025
Hua Peng
Professor, Guangzhou National Laboratory

Hua Peng, Ph.D., Principal Investigator at the Guangzhou National laboratory (GNL). Dr. Hua Peng graduated from Peking University, Health Science Center with a bachelor's degree, and completed his doctoral and postdoctoral training in virology at the State University of New York at Buffalo and the National Institutes of Health (LVD/NIAID/NIH). Prior to joining GNL, Dr. Peng held positions as associate Prof./Prof./PI at the Institute of Biophysics, Chinese Academy of Sciences. Her research focuses on 1) Investigating host immune response to virus infection, viral pathogenic mechanism, and virus-associated malignancy; and 2) Developing innovative preventive and therapeutic vaccines against viral infections and immune based anti-cancer drugs. Dr. Hua Peng has made important scientific and translational achievements, publishing in prestigious journals including Gut, Cell Res., Sci Immun., JEM, JCI, Gastro, Nat Commun., PNAS, Nat Med, Nat Immun., Hepatology, Clin Can Res, JI, JBC, and JV. Prof. Peng’s team invented a new-generation SARS-CoV-2 recombinant vaccine, leading to the approval of the vaccine product V-01 and its iterative vaccine BV-01-QX for emergency use in collaboration with Livzon Bio.


茶歇
From Design to lmmunogenicity: An Intranasal Respiratory Syncytial Virus Vaccine Targeting Prefusion F Protein
Vaccine Innovation Forum World 2025
Xiawei Wei
Professor, State Key Laboratory of Biotherapy, Sichuan University, China

Xiawei Wei, Professor, Changjiang Distinguished Professor, supported by National Science Foundation for Distinguished Young Scholars, graduated from the Department of Pharmaceutics of Zhejiang University in 2010 with a bachelor's degree, and graduated from the School of Pharmacy in Sichuan University with a doctor's degree. Currently, she is the director of the International office of West China Hospital, Sichuan University. She is the deputy director of the National Clinical Medical Center for Geriatric Diseases, and the director of Laboratory of Aging Research and Cancer Drug Target in West China Hospital. She is a committee member of ASGCT - American Society of Gene & Cell Therapy and the youth president of the Asia-Pacific Alliance for Gene and Cell Therapy. Her main research interests are development of recombinant protein vaccines and adjuvants, intranasal vaccine and mucosal delivery, and pulmonary inflammatory diseases and tumor immune microenvironment, as well as the translational research of small molecule anti-tumor drugs. She has published more than 110 papers in Nature, Nature Communications, EMBO Molecular Medicine, Advanced Science, Molecular Cancer, ACS Nano etc.(H-index=56). She has served as the Editorial Board Member or deputy editor of four SCI journals, and won the 2018 Yao Ming Kang De Scholar Award.

Swab and Spray: Precision Vaccination with Nasal Vaccines
Vaccine Innovation Forum World 2025
Ling Chen
PI, Guangzhou Laboratory

Dr. Chen has been a Professor at the State Key Lab of Respiratory Disease, Guangzhou Medical University since 2013. Dr. Chen received a medical degree from Shanghai Medical College in 1984. He obtained a Ph.D. in Biochemistry and Molecular Biology from Indiana University School of Medicine. Dr. Chen completed his postdoctoral training at Dana-Farber Cancer Institute, Harvard Medical School.  From 1997-2001, Dr. Chen served as a Senior Research Fellow at Merck Research Laboratories, where he was the first inventor of Merck's Ad5-based AIDS vaccine that entered clinical trials worldwide. Dr. Chen served as Vice President of R&D for GlaxoSmithKline in 2009-2011 and as Vice President at Sanofi Pasteur in 2012. Dr. Chen has over 200 publications in infectious diseases, vaccine research, and cancer research. His current research is focused on vaccine and antibody research on adenovirus, influenza virus, and emerging viruses. Since 2020, Dr. Chen has been working on developing user-friendly intranasal vaccines and mucosal immunity.

Lipid nanoparticles for mRNA vaccine delivery
Vaccine Innovation Forum World 2025
Norbert Pardi
Associate Professor, University of Pennsylvania, USA

Dr Norbert Pardi holds a Ph.D. in biochemistry and genetics. He has been working at the University of Pennsylvania since 2011 and currently holds an Assistant Professor position at the Department of Microbiology of the Perelman School of Medicine. His research interest is the development of mRNA-based therapeutics with particular focus on new generation infectious disease vaccines. He explored the development of a novel vaccine platform using nucleoside-modified mRNA in lipid nanoparticles (LNPs) and used it to generate highly effective vaccines targeting various pathogens (influenza virus, coronaviruses, malaria and others). Dr. Pardi is a pioneer of the nucleoside-modified mRNA vaccine technology and published milestone papers in the field.


Advanced quality control strategies for mRNA vaccines
Vaccine Innovation Forum World 2025
Heinrich Hass
CTO, NeoVAC, UK

Heinrich Haas, Department of Biopharmaceutics and Pharmaceutical Technology Johannes Gutenberg-Universität, Mainz Mainz, Germany. Ph.D. in the group of Prof. Dr. Helmuth Möhwald at Johannes-Gutenberg Universität Mainz. Researched lipid membranes and organized bio-molecular systems. In pharmaceutical industry (Munich Biotech, Medigene, BioNTech) developed different types of nanoparticle products to clinical stage. Focus on advanced approaches for nanoparticle development and control.

Formulation research and development of mRNA therapeutics based on stability, safety and accessibility
Vaccine Innovation Forum World 2025
Yafei Li
R&D Director, Rhegen Biotech, China

Dr. Yafei Li graduated from HKU Li Ka Shing Faculty of Medicine and is awarded of Nanshan Leading Talent. She mainly focuses on the research and development of nanomedicines and process development. She has published 6 papers in internationally renowned academic journals such as Cell Discovery, Small, and Nano Research, and has applied for more than 10 related patents. Currently, she works at Rhegen Biotech, where she is responsible for the formulation development. She led the establishment of the mRNA-LNP freeze-drying process platform and completed the development of the first domestic freeze-dried mRNA-LNP process that received an IND approval.


RNA platform implementation in Brasil: Seeding the innovation ecosystem in Latin America
Vaccine Innovation Forum World 2025
Patrícia Neves
Project Manager, mRNA center,Bio-Manguinhos/ Fiocruz, Brazil

Ph.D. in Cellular and Molecular Biology by Oswaldo Cruz Foundation and the AIDS Vaccine Research Lab (UW-Madison-USA). Currently, she manages the RNA Vaccine Development Partner Center for PAHO/WHO at Bio-Manguinhos-FIOCRUZ, focusing on the development and manufacturing of RNA-based vaccines and therapies in Brazil. This initiative aims for regional self-sufficiency in vaccine R&D and production, democratizing the RNA platform for Latin America and the Caribbean. Awarded by Women in Science of PDA Brazil (2021) and SIBEN-Argentina (2022), she has 18 years of experience in Immunology, Vaccine and Biotherapeuticals Development, Public Health, and Equity.

茶歇
mRNA vaccines and global health: addressing global unmet needs in infectious diseases
Vaccine Innovation Forum World 2025
Ruben Rizzi
Senior Vice President Global Regulatory Affairs,BioNTech, Germany

Ruben Rizzi, physician by training, SVP of Global Regulatory Affairs at BioNTech. I joined the company in December 2019 just before the pandemic, and I have been the global regulatory lead for BioNTech for our COVID-19 development. Currently, I am still supporting the lifecycle of our COVID-19 vaccine, and I am co-leading the Global Regulatory Affairs department at BioNTech and working closely with the teams that are responsible for the development of BioNTech´s pipeline, post-approval activities and labelling


Comprehensive LNP Characterization from Cargo to Target Modification by Nano-Flow Cytometry
Vaccine Innovation Forum World 2025
Na Wang
Application Engineer, NanoFCM

Na Wang, graduated from China Agricultural University and currently serves as an Application Engineer at NanoFCM Inc. Her responsibilities include application development and pre-sales technical support for nano-flow cytometry technology. She possesses a solid theoretical foundation and extensive characterization experience in the field of novel vaccine delivery systems.


Process Development for Circular RNA: Advancing Manufacturing Strategies
Vaccine Innovation Forum World 2025
Kaiyao Wei
Process Scientist,YXgene

Kaiyao Wei earned his bachelor's degree from China Pharmaceutical University and completed his master's and Ph.D. at Université Grenoble Alpes, France, specializing in Virology, Microbiology, and Immunology.

During his doctoral research, he focused on validating novel drug targets for anti-infective therapies, with expertise in high-throughput screening optimization and structural biology studies.

Since transitioning into the pharmaceutical industry, Dr. Wei has contributed to the early-stage development of six mRNA vaccines and therapeutics, including RSV (IND approved by the FDA), influenza, and acne vaccines. Currently, he is engaged in quality research and control for RNA-based therapeutics and delivery systems, with comprehensive experience spanning R&D to manufacturing quality management.

His professional focus includes analytical method development, lifecycle management, and product quality control, ensuring robust and regulatory-compliant analytical strategies.


Engineering Internal Architecture of Lipid Nanoparticles to Promote Efficient mRNA Endosomal Release
Vaccine Innovation Forum World 2025
Yuhong Cao
PI, the National Center of Nanoscience and Technology, China

Dr. Yuhong Cao is a scientist and principal investigator at the National Center of Nanoscience and Technology, Beijing, China. She earned her B.S. in Chemistry from Linfield College in Oregon, USA, and her Ph.D. in Materials Science and Engineering from Stanford University, California. Under the mentorship of Professor Nicholas Melosh, her doctoral research focused on developing a nondestructive nanostraw system for longitudinal living cell sampling. Following her Ph.D., Dr. Cao pursued postdoctoral training in T cell engineering by applying CRISPR-Cas technology. She worked with Professor Peidong Yang, in partnership with Professor Jennifer Doudna at the University of California, Berkeley. She then returned to Stanford University for a second postdoctoral fellowship with Professor Steven Chu, focusing on in vivo single-molecule tracking. At the National Center of Nanoscience and Technology, Dr. Cao leads a research group specializing in Nanomaterials and Plant Cell Surface Interfaces. Her work aims to develop universal intracellular delivery systems for natural plants to accelerate plant breeding. By exploring nanomaterials to facilitate effective gene editing using CRISPR technology, her lab addresses the critical need for efficient delivery systems in plants. This research has the potential to significantly shorten plant breeding cycles, enabling ultra-fast breeding and advancing agricultural innovation.



午餐
AI-Guided and Structure-Based Vaccine Design
Vaccine Innovation Forum World 2025
George Fu Gao
Professor, Chinese Academy of Sciences

George Fu Gao has been a key leader in the public health field, making remarkable contributions to research and discovery through basic research, clinical evaluation and advocacy. He has made many remarkable contributions to the scientific field of control and prevention of emerging infectious diseases. He obtained his DPhil degree from Oxford University, UK and did his postdoc work in both Oxford University and Harvard University (with a brief stay in Calgary University). Gao worked in Beijing Agricultural University (1986-1991), Oxford University (2001-2006), Institute of Microbiology, Chinese Academy Sciences (2004-2008, Director-General). China CDC (Director-General, 2017-2022), National Science Foundation of China (Vice-President, 2018-2022). Gao is a member (academician) of Chinese Academy of Sciences (CAS), an international member of the U.S. National Academy of Sciences (NAS), a foreign member of the U.K. Royal Society (RS), a member of the German National Academy of Sciences Leopoldina, a fellow of African Academy of Sciences and a fellow of The World Academy of Sciences (TWAS).


Structure-Based Vaccine Design: Innovations in Stabilizing Antigens and Addressing Emerging Viral Threats
Vaccine Innovation Forum World 2025
Shaowei Li
Professor, Xiamen University
Shaowei Li Ph.D. Professor of Biochemistry and Structural Vaccinology, Xiamen University Shaowei Li is a tenured Professor of Biochemistry and Structural Vaccinology in the School of Life Sciences with a joint appointment in the School of Public Health, Xiamen University, China. He is the vaccine group leader in the National Institute of Diagnostics and Vaccine Development in infectious diseases (NIDVD), one of the academic leaders in the State Key Laboratory of Molecular Vaccinology and Diagnostics, deputy director in Fujian provincial Xiang An biomedicine laboratory. Dr. Li has inter-disciplinary research interests focusing on structural vaccinology, resulting in more than 120 peer-reviewed papers. He also has translational experience in vaccine development against infectious diseases—such as Hepatitis E vaccine and HPV vaccine, especially in aspects of immunogen design, process development and antigen characterization. Dr. Li has won two of China’s National Science and Technology Awards and been listed in the Top 20 translational researchers of 2016, ranked by Nature Biotechnology. He has served on the Product Development for Vaccines Advisory Committee (PDVAC), World Health Organization (WHO) since 2022.
Proteolysis-Targeting Live Vaccine Technologies
Vaccine Innovation Forum World 2025
Longlong Si
Professor, Shenzhen Institute of Advanced Technology, CAS, China

Longlong Si is a professor in the Institute of Synthetic Biology at Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), and the associated director of State Key Laboratory of Quantitative Synthetic Biology. Before joining SIAT, he was a Wyss Technology Development Fellow and postdoctoral research fellow in the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School. He received his Ph.D. in Chemical Biology from Peking University and his bachelor’s degree in Pharmacy from West China School of Pharmacy, Sichuan University. Si Lab’s research interests lie at the interface of synthetic biology and virology/vaccinology/biomedical engineering, and they have focused on Synthetic Biology-Inspired Virus Engineering for Medical Innovation, Human Organ-on-a-Chip Technology Development and Applications, as well as Translating the Innovations into Commercial Products. He has authored about 50 publications and his representative accomplishments have been published in Science, Nature Biotechnology, Nature Microbiology, Nature Biomedical Engineering, Nature Chemical Biology, Science Advances, Nature Communications etc. He has filed more than 20 patents, including antiviral drugs that are under testing in Phase II clinical trial. Part of the findings and technologies were awarded “Top 10 Scientific Progress of China in 2017”, “International Society for Vaccines (ISV)-Paper of the Year”, and “Wyss Technology Development Fellowship”. In 2024, he was included in "World's Top 2% Scientist List" released by Standford University and Elsevier.  

Bioassay for vaccine efficacy
茶歇
AI-assisted vaccine and adjuvant design by immunoswithing technology
Vaccine Innovation Forum World 2025
Ken Ishii
Director, International Vaccine Design Center, Professor, University of Tokyo, Japan
Characterization of structural biology and immunology of virus-like structure vaccine
Vaccine Innovation Forum World 2025
Qihan Li
Professor, Weirui Bio, China
A path toward broadly and durably protective vaccines
Vaccine Innovation Forum World 2025
Yoshimasa Takahashi
Director,National Institute of Infectious Diseases, Japan

Yoshimasa Takahashi, PhD, graduated from University of Tokyo. He received his postdoctoral training at the University of Maryland at Baltimore, where he worked on understanding the basic mechanisms for humoral immune memory and antibody responses. He joined the National Institute of Infectious Diseases (NIID) in Japan, and became Director at the Department of Immunology. He was appointed to Director of the Research Center for Drug and Vaccine Development, NIID in 2021. He also holds the position of Guest Professor at seven universities. In this role, he trains graduate students in Immunology and Vaccinology.

Dr. Takahashi's research focuses on comprehending lymphocyte biology to unravel the humoral and cellular immune responses that underly vaccine effectiveness. By implementing high-throughput approach for human antibody analysis and isolation, he has identified novel classes of broadly protective antibodies against influenza, SARS-CoV-2, and other viruses. Multiple R & D for next-generation of vaccines and antibody therapeutics are on-going based on these findings.


Malaria Vaccines: from Licensure to Elimination
Vaccine Innovation Forum World 2025
Adrian V. S. Hill
Director, The Jenner Institute, Professor, University of Oxford , UK

Professor Adrian V. S. Hill FRS is the Director and Founder of the Jenner Institute, and Mital Professor of Vaccinology at Oxford University. He is a passionate believer in the power of molecular medicine to address many of the most egregious health care inequities globally. His group have been leaders in the development of adenoviral and other vaccines against infectious diseases and he has tested these in extensively in over eighty clinical trials in Africa and Europe. In partnership with the Serum Institute of India and AstraZeneca the Jenner Institute developed rapidly a ChAdOx1 vector-based SARS-CoV-2 vaccine which saved an estimated 6.2 million lives in 2021 alone.

His lab also designed a newly licensed high efficacy malaria vaccine, R21/Matrix-MTM, which has recently shown unprecedented high efficacy in a phase III trial in four African countries, again in partnership with the Serum Institute of India and also Novavax Inc. This vaccine promises to make a major impact on reducing the 500,000 childhood deaths from malaria each year. In 2021 he was elected a Fellow of the Royal Society and is a Knight Commander of the Order of the British Empire (KBE).



Rational design of Zika vaccine to eliminate dengue enhancement
Vaccine Innovation Forum World 2025
Lianpan Dai
Principle Investigator, Institute of Microbiology, CAS, China

Lianpan Dai, PhD, Principal Investigator at Institute of Microbiology, Chinese Academy of Sciences. He received his doctor's degree from Technical University of Munich (TUM), Germany. His research is mainly focused on the design and development of novel vaccines against major pathogens and the mechanism of protective immune response. Important research and translational achievements have been made in the research and development of vaccines against coronaviruses, Zika virus and other emerging infectious diseases, among which the recombinant protein subunit COVID-19 vaccine has been approved for use in many countries. The results are published as first/corresponding authors in the journals including Cell, The New England Journal of Medicine, Lancet, Nature Immunology, Nature Reviews Immunology, Cell Host & Microbe. He is supported by the National Science Fund for Excellent Young Scholars, and is the winner of VCANBIO Award for Biosciences and Medicine, excellent member of the Innovation Promotion Association of Chinese Academy of Sciences, the Young Scholar Award of Chinese Society of Immunology, and China Patent Silver Award Winner.


Innovative immunogen design for mpox virus vaccine development
Vaccine Innovation Forum World 2025
Han Wang
Associate Professor, Peking University

Han Wang, PhD, Associate Research Professor at the College of Future Technology, Peking University. She received her doctor's degree from the Institute of Microbiology, Chinese Academy of Sciences. Her research is mainly focused on virus infection and the development of antiviral agents and novel vaccines. Important research and translational achievements have been made in the study of Ebola virus entry, nucleo-cytoplasmic large DNA virus (NCLDV) replication, and the development of novel vaccine against mpox virus. The results have been published as first/corresponding author in the journals including Cell, Nature Immunology, PNAS, Nucleic Acids Research. She was selected and supported by Postdoctoral Innovation Talents Support Program and Beijing Municipal Supporting Project for Young Talents (2022-2024), was a member of the Innovation Promotion Association of Chinese Academy of Sciences, and is currently a young editorial board member of hLife journal.


Harnessing Opportunities: Unlocking the Potential for Clinical Trials in Africa
Vaccine Innovation Forum World 2025
Christopher Obwanga
East Africa Regional Manager, P-95, Nigeria

Christopher Obwanga is currently the East Africa Regional Manager at P95 Africa, bringing over 15 years of experience in clinical trials within the EMEA region, with a particular focus on sub-Saharan Africa.  Throughout his career, Christopher has held multiple roles including leadership positions at IQVIA and Roche.  


茶歇
Efficacy safety and immunogenicity of hexavalent rotavirus vaccine in China
Vaccine Innovation Forum World 2025
Gelin Xu
Senior expert,Wuhan Institute of Biological Products ltd co.

Dr. Xu Gelin, senior  expert of  Wuhan Institute of Biological Products (WIBP), experienced on vaccine development for nearly 40 years. 

Assembly of Virus-like Particles Harnessed with RNA-based Chaperone
Vaccine Innovation Forum World 2025
Baik-Lin Seong
Director General, Vaccine Innovative Technology ALliance (VITAL)-Korea

Baik-Lin Seong, PhD, is a Distinguished Professor of Yonsei University College of Medicine, and Director General of Vaccine Innovative Technology ALliance (VITAL)-Korea. He received B.S. from Seoul National University (1977), M.S. from KAIST (1979), PhD from MIT (1988). He worked as postdoctoral scientist at the University of Oxford (1988-1992).

He served as a member of the Presidential Advisory Council of Science & Technology of Korean Government (2021-2022) and the Scientific Advisory Board of International Vaccine Institute (IVI) (2018-2022). He chaired the COVID-19 Vaccine Pan-Government Strategic Plan of the Korean Government (2020-2023).

With a view to ensure equitable access of effective vaccines to LMICs, he works on developing a low-cost production platform of VLP/nanoparticle vaccines against RSV, norovirus, nipah, universal influenza vaccine, and flavivirus vaccines including Japanese Encephalitis, Zika, and West Nile viruses.


A quadrivalent mRNA vaccine candidate elicited potent immune responses against monkeypox virus and protection in a rodent model
Vaccine Innovation Forum World 2025
Yelin Xiong
VP, Yither Biotech Shanghai/Zhonghui Yuantong Bio Jiangsu, China

Dr. Yelin Xiong is the Vice President at Yither Biotech Co. Ltd. In this role, she is responsible for early-stage discovery to clinical material manufacturing of various vaccine candidates. Yelin has extensive research experience in immunology and vaccine development against infectious diseases. Prior to the current position, Yelin had over 20 years of industry experience in research, process development/scale-up, GMP manufacturing and CMC management in Sanofi pasteur. She received a Doctorate degree in Immunology and Cell Biology from John Curtin School of Medical Research, Australian National University and had postdoctoral training in Emory University and University of Toronto.          


The urgent need for new combination vaccines
Vaccine Innovation Forum World 2025
Christopher Gill
Senior Program Officer, Vaccine Clinical Developmenta Gates Foundation, UK

Christopher Gill has an MD from the University of Massachusetts Medical School and an MS from the Tufts School of Graduate Biomedical Studies.  Dr. Gill is an infectious disease specialist by training. From 2002-2008 and again from 2011-2023 he was a faculty member of the Department of Global Health at Boston University School of Public Health rising eventually to the level of full professor of Global Health.  During the intervening years 2008-11 he was the clinical director for the development of the MenACWY-CRM conjugate meningitis vaccine for Novartis Vaccines and Diagnostics. His work has centered broadly on child-survival in the areas of diarrheal diseases, pneumonia, and neonatal survival. However, his largest concentration of work has focused on better understanding the epidemiology of pediatric respiratory infections, notably Streptococcus pneumoniae, Bordetella pertussis and Respiratory Syncytial Virus.  At BU, Dr. Gill was the 2015 recipient of the Norman Scotch Award for excellence in teaching at Boston University School of Public Health, and the 2016 recipient of Boston University's Metcalf Cup and Prize. The Metcalf Cup and Prize is BU's highest teaching honor and is awarded to one of BU's >3500 faculty across its 17 colleges and schools each year.  At the Gates Foundation, Dr. Gill’s main areas are development of combination vaccines and expanding the impact of HPV vaccination globally. 


Rational design and generation of a noval recombinant Pseduomonas areaginosal subunit vaccine
Vaccine Innovation Forum World 2025
Jiang Gu
Professor, Vice Director, Army Medical University

Professor Jiang Gu is the Deputy Director of the National Engineering Technology Research Center for Immunological Biopreparations at the Army Medical University. He serves as the Chief Scientist for a national key research and development program,and has earned the First Grade Prize for Technological Invention in Chongqing and the Second Grade Prize for Military Science and Technology Progress.

His primary research focuses on the fundamental and clinical applications of structural vaccinology, particularly in immune interventions against multidrug-resistant bacteria. Notably, he has spearheaded the development and commercialization of a Class 1.1 innovative new drug, a genetically engineered Pseudomonas aeruginosa vaccine, which has achieved a technology transfer agreement valued at 2.8 billion yuan.


TBD-Wuxi Vaccines
Harnessing mRNA Technology to Combat Antimicrobial Resistance: Pioneering Vaccines for Drug-Resistant Bacteria
Vaccine Innovation Forum World 2025
Caiyi Fei
Co-founder& VP, Therarna

Graduated with a Ph.D. in Bioinformatics from the University of Science and Technology of China in 2014, under the guidance of Professor Liu Haiyan. Many years of experiences in molecular dynamics simulation and high-throughput sequencing, and have served as the Director of Bioinformatics for Micro Spin Genes and the Head of Nucleic Acid Drug Development for Yidu Cloud. Successfully developed multiple clinical high-throughput data analysis platforms and have authored multiple invention patent authorizations and SCI papers. As the co-founder of Therarna, responsible for identifying and optimizing upstream targets of mRNA drugs, leading the team to develop a systematic platform for identifying cross species cellular immune epitopes, designing humoral immune antigens, and optimizing mRNA sequences.

茶歇
Isolation of protective monoclonal antibodies and development of novel fusion protein vaccines against tuberculosis
Vaccine Innovation Forum World 2025
Hao Li
Associate Professor, China Agricultural University

Hao Li is an associate professor and PhD supervisor at the College of Veterinary Medicine, China Agricultural University. He received his PhD degree from Tsinghua University in July 2017. From July 2017 to July 2019, he did his postdoctoral research at the School of Medicine, Tsinghua University. From July 2019 to now, he has worked at China Agricultural University and focused on tuberculosis immunology, TB vaccine development, and antibiotic resistance. He has published more than 30 articles in Nature Reviews Immunology, PNAS, Nature Communications, npj Vaccines, and other journals. Dr. Li serves as guest editor and youth editorial board member for multiple journals and as a reviewer for some journals and several grant agencies.


More than a theory - Successful vaccination by Micro Array Patches
Vaccine Innovation Forum World 2025
Markus Winterberg
Head, Analytical Development, Microbiology, Quality Control – MAP Program, LTS, Germany

Markus is Head of Analytical Development, Microbiology, and Quality Control for the MAP-Program at LTS Lohmann Therapie Systeme AG in Andernach. He studied biology at Philipps University in Marburg, Germany, and was awarded a PhD in Parasitology in 2009 for his work on the membrane physiology and biochemistry of the Malaria parasite. From 2009 to 2015 he expanded his track record in infectious disease research at The Australian National University in Canberra, Australia. In 2015, he accepted a position for the University of Oxford, leading the Clinical Pharmacology laboratories at the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. In 2019 he joined LTS as Head of Analytical Development, Microbiology and Quality Control for the MAP Program.


A High-Density Microarray Patch (HD-MAP) to Improve Effectiveness of Vaccines
Vaccine Innovation Forum World 2025
Thomas Lake
SVP Vaccine Alliances, Vaxxas, Autralia

Mr. Lake has worked in vaccine manufacturing and commercialization for 30 years developing diverse experience at global leaders Merck and GlaxoSmithKline. Mr. Lake's background includes live virus and recombinant vaccine bulk production, sterile filling, and quality control, before moving into product management and business development roles. He served as the manufacturing Alliance Manager between Merck and Sanofi Pasteur during the startup of their European loint Venture and worked for several years as asenior level commercialization consultant in the vaccine industry.

Mechanisms of vaccine reactogenicity
Vaccine Innovation Forum World 2025
Arnaud Didierlaurent
Assistant Professor, Director of Center of Vaccinology,University of Geneva

Arnaud Didierlaurent is an engineer in Biotechnology by training and an immunologist with a PhD in cellular immunology from the University of Lausanne in 2003 (Jean-Pierre Kraehenbuhl). Arnaud continued his work on innate immunity in the lab of Jürg Tschopp before joining the Imperial College, London, where he worked as postdoctoral fellow from 2004 to 2007 on the long-term impact of viral infection on the lungs. He was also a research fellow in Ralph Steinman's lab at the Rockefeller University in New York. Arnaud then joined the R&D department of GlaxoSmithKline in 2008 in Belgium, where he held several leading positions in vaccine research and development. Initially head of a lab investigating the mode of action of adjuvant, Arnaud became in charge of the GSK Adjuvant System portfolio and thus directly involved in the licensure of several adjuvanted vaccines.

Arnaud’s scientific contributions have consequently been focused on deciphering the interplay between innate immunity and pathogen/vaccine-specific adaptive response. With his experience in both academic and industrial settings, Arnaud has acquired a deep understanding of how vaccines are created, developed and deployed. He joined the University of Geneva in March 2020 to continue his work on translational vaccine research. He is acting as the chairman of the WHO Technical Advisory Group who provides recommendations for the Emergency Use listing of COVID-19 vaccine candidates. Since February 2023, he is an associate professor and the director of the Center of Vaccinology at the Faculty of medicine. 


Revolutionizing Therapeutics with Next-Generation RNA Platforms: From Vaccines to Gene Therapy (TBD)
Vaccine Innovation Forum World 2025
Zihao Wang
CEO, Immorna Biotherapeutics

After obtaining his PhD in Biological Chemistry from the Johns Hopkins University, Dr. Wang started his industry career and worked at a number of biotech and pharmaceutical companies, including Grifols S.A., Novartis, and GSK Vaccines, during which he rose from scientist to leadership roles and accumulated rich vaccine and drug development experience, especially with self-replicating RNA. After leaving GSK, Dr. Wang co-founded Immorna Biotherapeutics. Under his leadership, Immorna has built cutting-edge and proprietary mRNA platform technologies and developed rich clinical pipeline spanning infectious diseases, immune-oncology, and rare genetic disease areas.


Rational design of ionizable lipids for RNA delivery
Vaccine Innovation Forum World 2025
Xuexiang Han
Professor, SIBCB, China

Professor Han Xuexiang is a researcher, project leader and doctoral supervisor of the Center of Excellence in Molecular and Cell Science, Chinese Academy of Sciences.

Selected in the national high-level talents (overseas) project and Shanghai Leading Talents (overseas) project.

Hanz Biotechnology (Suzhou) Co., LTD., Co-founder & CSO.

He received his bachelor's degree from Shanghai University in 2014, and his PhD from Tsinghua University in 2019 (jointly trained by National Center for Nanoscience and Technology). From 2020 to 2024, he worked as a postdoctoral researcher in the laboratory of Professor Michael J. Mitchell, University of Pennsylvania, USA, during which he collaborated with Professor Drew Weissman, winner of the Nobel Prize, on the research of LNP-mRNA vaccines and drugs. In February 2024, he joined the Center of Excellence in Molecular and Cell Science, Chinese Academy of Sciences. His research focuses on the construction of novel LNP and RNA drug delivery. He is the first-author (including co-first author) of Nat.Chem., Nat.Nanotech., Nat.Mater., Nat.Commun. He has published nearly 20 papers in other journals, authorized one Chinese patent, and applied for a number of PCT patents.


Scaling Up the Next RNA Frontier: Strategy & Innovations in Large-Scale circRNA Manufacturing
Vaccine Innovation Forum World 2025
Yongbo Xue
Senior Research Scientist, BiosynRNA Biotechnology

PhD in Cellular and Molecular Biology, University of Nevada

10 years of R&D experience and 5 years of industry experience

Published over 10 academic research articles

Plenty of experience at mRNA/ circRNA construction, genome editing and stem cell therapy


Non-reactogenic LNPs addressing mRNA vaccination hesitancy
Vaccine Innovation Forum World 2025
Jiangsheng Xu
Founder& CSO, General Therapeutics, USA

Dr. Jiangsheng Xu is the Founder and Chief Scientific Officer of General Therapeutics, Inc., specializing in the development of non-reactogenic lipid nanoparticle (LNP) technologies aimed at overcoming challenges in mRNA vaccine hesitancy and RNA medicine re-dosing. With over 15 years of hands-on experience in nanoparticle and RNA research across both academic and industry settings, Dr. Xu has contributed to leading journals, including Nature Nanotechnologyand Nature Communications, and holds 10 patents.

茶歇
Pre-clinical development of a circular RNA vaccine against Nipah virus
Vaccine Innovation Forum World 2025
Pei-Yin Lim
Senior Manager, Preclinical R&D, Hilleman Laboratories, Singapore

Pei-Yin is leading the Preclinical R&D at Hilleman Laboratories. She has more than 20 years of experience in virology and close to 10 years of experience in vaccine development. She obtained her PhD from University of Wisconsin-Madison, and pursued her postdoctoral training at Wadsworth Center, New York State Department of Health and the University of Wisconsin-Madison. Her industry experience started when she joined Sentinext Therapeutics in Malaysia, developing vaccines against enteroviruses. After Sentinext, she joined Singapore Immunology Network (SIgN), A*STAR, Singapore to develop therapeutic antibodies against viruses. She joined Hilleman Laboratories in 2021 as a Senior Scientist, and is currently the Senior Manager at Hilleman leading the Preclinical team.

Optimizations of VZV mRNA vaccine
Vaccine Innovation Forum World 2025
Wenshuo Zhou
Leading Scientist & CSO Academic Secretary, CNBG- Virogin Biotech, China

Ph.D. Old Dominion University, Virginia. USA, concentrated on vector-borne disease.

ORISE fellow, The US Food and Drug Administration, CBER,DVP, OVRR.

 

An expert on Flaviviridae vector-borne diseases including LGTV, ZIKV, DENV infection and transmission through the facilitation of exosome and published on several top journals (PNAS, EMI, PLoS Pathog, etc.).

ORISE fellow at the FDA, worked on live attenuated Rubella vector vaccines expressing RSV, Covid-19 or HIV interest proteins.

Now working as a leading scientist & academic secretary of CNBG-Virogin, leading POC research team and be responsible for all the infectious disease mRNA vaccine pipelines that under the POC stage.


Optimizing Tissue Distribution & Safety of LNP-Mediated Prophylactic Vaccines to Accelerate Prevention of Infection & Disease
Vaccine Innovation Forum World 2025
Hui Li
R&D Director, Innorna

Dr. Hui  Li is a dedicated professional who is currently serving as the Director of  R&D at Innorna. Her work specializes in the research and development of  vaccines for infectious diseases. With her vast experience in the life  sciences industry, she has been involved in numerous vaccine development  projects and has conducted extensive research in this field. As a leader of  the vaccine R&D team at Innorna, Hui continuously innovates and has  successfully developed several mRNA infectious disease vaccines, which are currently undergoing clinical trials.  Founded in 2019, Innorna is a platform-based delivery technology company primarily focused on developing nucleic acid drug delivery technologies. It is among the few global high-tech firms that have mastered the LNP technology, with a proprietary mRNA platform technology. Leveraging the LNP and mRNA platform technologies, Innorna has developed pipelines for infectious disease vaccines, rare diseases, and tumor immunotherapies.

Innovative Delivery Methods for Next-Generation Vaccines: Nasal, Inhalable, and Beyond
Vaccine Innovation Forum World 2025
SeyedReza Banihashemi
Director of R&D, Razi Vaccine & Serum Research Institute

Dr. SeyedReza Banihashemi is the Head of Immunology Department and an Assistant Professor at Razi Vaccine and Serum Research Institute in Karaj, Iran. He holds a Ph.D. in Clinical Immunology from Tarbiat Modares University, Tehran.  With over 20 years of experience in vaccine research and development, Dr. Banihashemi designed and developed Razi Cov-Pars, Iran's domestically produced COVID-19 vaccine. Under his leadership, Razi Institute successfully conducted Phase 1, 2 and 3 clinical trials of Razi Cov-Pars.this vaccine is first intranasal covid 19 vaccine in the world.

His research focuses on mucosal Immunity , intranasal vaccine , adjuvants, drug delivery systems, immune regulation and the development of bacterial and viral vaccines. He has published over 50 papers and authored book chapters in his field. His work on nanobody technology and immunoliposomes has applications for targeted drug delivery.

In addition to conducting research, Dr. Banihashemi teaches courses in infection and immunity. He has received several awards for his scientific contributions, including for exemplary research from Razi Institute. 

When not engaged in his own work, Dr. Banihashemi reviews papers for international journals. 


The Molecular Clamp Platform: A broadly applicable solution to the manufacture of multivalent subunit vaccines for respiratory viruses
Vaccine Innovation Forum World 2025
Keith Chappel
Group Lead, The University of Queensland, Australia

Prof Keith Chappell

Australian Institute for Bioengineering and Nanotechnology, and School of Chemistry and Molecular Biosciences, The University of Queensland, Australia

 

Prof Keith Chappell is a Molecular Virologist whose research is focused on structure-based design of vaccines for medically important viruses. Keith is one of the inventors of the broadly applicable vaccine platform, molecular clamp. Molecular clamp locks viral glycoproteins into the native prefusion conformation to elicit highly protective immunity and enables consistent manufacture of highly stable, ready-to-use, fully liquid vaccines. Keith leads a team of 20 staff and students split across two major research programs: The CEPI funded Rapid Response Vaccine Pipeline which seeks to safeguard against future pandemics and contract research conducted for the UQ biotech spinout company Vicebio Ltd. In 2020, Keith co-led the University of Queensland’s effort to produce a covid vaccine, which progressed from sequence information to clinical trial dosing within 6 months, however did not progress due to interference with some existing HIV diagnostic tests. Since that time this team as produced a new covid vaccine incorporating a second-generation molecular clamp that has completed clinical testing showing favourable safety and immunogenicity profile in comparison to approved covid vaccine, Nuvaxovid (Novavax). Vicebio is also actively advancing this technology for the development of multivalent vaccine formulations to target life-threatening respiratory viruses, with a bivalent vaccine for Respiratory Syncytial virus and human metapneumovirus is currently undergoing phase I clinical trial testing.


An economical adjuvant without production limit to induce potent cell-mediated immunity in subunit vaccines
Vaccine Innovation Forum World 2025
Cunbao Liu
Professor, Institute of Medical Biology, CAMS&PUMC, China

Dr. Cunbao Liu is full professor at the Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, PI of the National Key R&D Program Young Scientist Project in China. In recent years, he has published dozens of research papers as the first/corresponding author, authorized 5 domestic invention patents. Dr. Liu’s lab mainly focuses on the research and development of novel adjuvant-based subunit vaccines and mRNA vaccines, especially the contribution of cell-mediated immunity (CMI)induced by such vaccines. CMI is critical for vaccines targeting to latent infection pathogens (e.g. herpes virus and rabies virus), and maybe helpful for vaccines targeting to mucosal infection pathogens (e.g. SARS-CoV-2 and respiratory syncytial virus that invade through respiratory tract, or rotavirus and norovirus that invade through gastrointestinal tract). His topic today is “An economical adjuvant without production limit to induce potent cell-medicated immunity in subunit vaccines”.


Amezosvatein Phase 2 trial results
Vaccine Innovation Forum World 2025
George Simeon
CEO, Curevo Vaccine

George Simeon is the CEO of Curevo Vaccine. He joined Curevo at the beginning of 2019 and has over 30 years of experience in the healthcare sector working with multinational firms, start-ups, and not-for-profits. He has worked in biotech, pharmaceuticals, medical devices, IVD, and healthcare convergence technologies. He has worked extensively in Europe, Asia, and North America.

Before moving to the USA, he was based in South Korea from 2014-2018, where he worked for SK Telecom’s Healthcare Division in M&A and global strategic alliances. In 2016, he joined Sollers Partners, a cross-border investment advisory firm, while maintaining an advisory role with SK Telecom.

He has worked across Europe and the USA as an executive with Johnson & Johnson, as the founding Vice-President of Cordis Neurovascular Europe, and with GHX Europe as a Commercial Vice-President. He also spent 3 years with Novartis Global Headquarters in Switzerland working on projects in their CNS portfolio in Health Economics and Pricing.

George has also founded two start-ups and advised GS1 on their global entry and expansion into the Healthcare, High-Tech, and Customs sectors as well as on ESG practices in FMCG logistics.

George is a graduate of INSEAD (MBA) and Yale University (MPH).



茶歇
Innovating Plant-Based Vaccines: A New Frontier in Global Health
Vaccine Innovation Forum World 2025
Suthira Taychakhoonavudh
CEO, Baiya Phytopharm, Thailand
Revolutionizing Pneumococcal Vaccination: Advancing Towards a Universal Pneumococcal Vaccine Solution
Vaccine Innovation Forum World 2025
Tim Hirst
Chairman & CEO, GPN Vaccines
Vaccine development based on DDS technology
Vaccine Innovation Forum World 2025
Yasuo Yoshioka
Project Leader, BIKEN Center for Innovative Vaccine Research and Development, Japan

Yasuo Yoshioka, PhD

Group Leader,The Research Foundation for Microbial Diseases of Osaka University

  

Education;              

1995-1999; Faculty of Pharmaceutical Sciences, Osaka University (Awarded the degree of B.S.).

1999-2001; Graduate School of Pharmaceutical Sciences, Osaka University (Awarded the degree of M.S.).

2001-2004; Graduate School of Pharmaceutical Sciences, Osaka University (2004; Awarded the degree of Ph.D. from Osaka University)

 

Brief chronology of employment;

2004-2006; Research Scientist, National Institute of Health Sciences (Tokyo, Japan)

2006-2012; Specially Appointed Associate Professor, The Center for Advanced Medical Engineering and Informatics, Osaka University (Osaka, Japan)

2012-2014; Associate Professor, Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University (Osaka, Japan)

2015-2020; Specially Appointed Associate Professor, Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University (Osaka, Japan)

2020-2024; Specially Appointed Professor, Vaccine Creation Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University (Osaka, Japan)

2015-Present: Group leader, The Research Foundation for Microbial Diseases of Osaka University (Osaka, Japan)



Nanotechnology in Vaccine Development: Transforming Delivery and Efficacy
Vaccine Innovation Forum World 2025
Chunying Chen
Academician, Professor, The National Center for Nanoscience and Technology,CAS, China
Empowering the Immunity: CpG adjuvants for vaccine development and cancer therapy
Vaccine Innovation Forum World 2025
Jon Wang
R&D President / CSO,Parr Biotechnology

Dr. Xinzhong (Jon) Wang, Ph.D. currently serves as the Global R&D President and CSO of Parr Biotechnology (He Bei) Co. Ltd.

 

He was the Founder and CEO of Fusion Bioscience (Cayman) Inc. incorporated in November 2021.  Fusion Bioscience merged with Parr Bio in 2023. Dr. Wang is a scientific leader with over 20 years of experience in oncology research and drug development. He has extensive knowledge and experience in tumor immunology, molecular and cell biology, drug target discovery, animal modeling, and protein therapeutics development. He has published more than 30 original scientific papers in prestigious journals and is the inventor of several international patents.

 

Prior to Parr Bio, Dr. Wang served as Senior Vice President and Chief Scientific Officer at CStone Pharmaceuticals (HK02616); Director of Immuno-Oncology research at Merck & Co.; Associate Director of BioSuperiors at AstraZeneca/MedImmune;  Principal Scientist at Biogen.

Dr. Wang obtained a Bachelor of Science degree in Biochemistry from Nankai University and a PhD in Molecular and Cellular Biology from Ohio University. He completed his post-doctoral training in Gene Therapy at Harvard Medical School/Massachusetts General Hospital and subsequently served as an Instructor of Medicine at Harvard Medical School.


Next Generation of Highly Effective Adjuvant Systems: Safe & Efficacious Vaccines Made Possible Through Partnerships, with Inimmune and SPI Pharma
Vaccine Innovation Forum World 2025
Juhienah Khalaf
Director of Chemistry, Inimmune Corp

Juhienah Khalaf is a medicinal chemist with expertise in the synthesis and development of bioactive compounds, including antifungal agents, immunomodulators, and protease inhibitors. With a strong background in organic and combinatorial chemistry, Juhienah has contributed to advancing research in therapeutic molecules targeting immune responses and infectious diseases. Her work spans the design and synthesis of TLR4 agonists, small-molecule drugs, and immuno-based therapeutics. Juhienah's research has been instrumental in the development of novel adjuvant systems and targeted therapies, aiming to address critical challenges in immunology and infectious disease treatment.  Juhienah first synthesized INI-2002, a TLR4 agonist that has become the lead component in Inimmune's Adjuvant Systems. This work is presented at the Vaccine Industry Forum (VIF) conference, highlighting its potential in enhancing vaccine efficacy through targeted immune modulation.

Enhancing Mucosal Immunity with RAR Agonists as Potent Vaccine Adjuvants
Vaccine Innovation Forum World 2025
Haibo Li
Professor, Army Medical University, China
Dr. Haibo Li is a professor in the National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, Army Medical University (Third Military Medical University). He obtained his PhD in biological technology from Third Military Medical University in 2013. His current research activities focus on integrating chemical synthesis and immunology to discover novel mucosal vaccine adjuvants. He developed an original strategy to rationally design novel lipopeptides as mucosal adjuvants by mimicking the active sites of the bacterial lipoproteins. Dr. Li has published over 50 peer-reviewed papers and several books and book chapters. Now he is a council member of Chongqing Pharmacological Society.
茶歇
Harnessing the power of TLR agonists as vaccine adjuvants
Vaccine Innovation Forum World 2025
Nikolai Petrovsky
Founder, Vaxine, Australia
Professor Nikolai Petrovsky is a physician and vaccine researcher. He is the founder of Vaxine, an Australian biotechnology company applying novel approaches including artificial intelligence to vaccine and adjuvant development. His research has been awarded multi-million dollar contracts from the US National Institutes of Health and he has authored over 200 peer-reviewed research papers. He developed SpikoGen®, a vaccine against COVID-19 that received emergency use authorization in the Middle East in October 2021, making it the first recombinant protein vaccine against COVID-19 to achieve regulatory approval.
Reserved by Adjane, Netherlands
Nanoemulsion Adjuvants
Vaccine Innovation Forum World 2025
Yongming Chen
Professor, Sun Yat-sen University

Yongming Chen received his Master degree of chemistry in 1990 from Northwest University, Xian. In 1993, he obtained his Ph.D. on polymer science from Nankai University, Tianjin. From 1994 to 1998, he was Postdoctoral Researcher and later Research Assistant at the Institute of Chemistry, CAS. Then he spent the period 1998−2001 as Postdoctoral Researcher in the University of Düsseldorf and the University of Mainz. Since 2001, Chen was Professor at the Institute of Chemistry CAS. He moved to Sun Yat-sen University in 2013 and he works in Henan University in 2024. He obtained the “Distinguished Young Scholars” by the National Science Foundation of China (2006) and the “Wang Bo-Ren Polymer Research Award” by the Chinese Chemistry Society (2011). He served for Polymer, an Elsevier journal as an Associate Editor from 2007 to 2018. He also was on the Advisory Board Panel of Macromolecules and ACS Macro Letters. Professor Chen’s research interests are in the areas of synthesis methodology of polymers and polymer application in nanomedicine on biologics delivery, immune activation and inhibition. He has published over 300 research articles and around 30 patents approved.


Engineered design of aluminum-based combination adjuvants
Vaccine Innovation Forum World 2025
Bingbing Sun
Professor, Dalian University of Technology, China
Dr. Bingbing Sun received B.S. and M.S. in Chemical Engineering from Dalian University of Technology (DUT), and a Ph.D. in Chemical Engineering from the University of Washington. He had his postdoctoral training at the University of California's Center for Environmental Implications of Nanotechnology (UC-CEIN) at the University of California, Los Angeles (UCLA). He starts his academic career in the School of Chemical Engineering at DUT in 2016. Currently, he is a full professor and serves as the chair of the Department of Chemical Engineering at DUT. His research interest includes vaccine adjuvants, formulation, biomaterials, nano-bio interface, and immunoengineering. He serves as earlier career researchers editorial board of BMEMat.
Clinical data of single dose vaccine development for Rabies
Vaccine Innovation Forum World 2025
Sandy Douglas
Associate Professor, Oxford University, UK
Efficacy and safety of a herpes zoster vaccine in clinical trial in China
Vaccine Innovation Forum World 2025
Jingxin Li
Deputy Department Head, Jiangsu CDC, China

Jingxin Li, PhD, Professor, is working at Jiangsu Provincial Center for Disease Control and Prevention. Her research is focused on vaccine clinical evaluation and immunization strategy. She has participated in a lot of epidemiology investigations and a series of clinical trials of novel vaccines, including Enterovirus type 71 vaccine, recombinant human Ad5 vectored Ebola vaccine, and Covid-19 vaccines. She has got National Natural Science Outstanding Youth Founds and Jiangsu Provincial Natural Science Funds for Distinguished youths, and hosted or participated in seven National Natural Science Founds or National Science and Technology Major Projects. She has published over 25 articles in medical journals on vaccine clinical studies, including Nature Med, Lancet Respir Med, Lancet Glob Health, etc.


Global Vaccine Registration Strategy and Key Considerations
Vaccine Innovation Forum World 2025
Howard Yuwen
SVP & CBO, SDM Bioservices, China

35 years of industry experience 

Former executive at global companies in China, the US, and Europe, including Amador, Worg, Alexion (AstraZeneca), Shire (Takeda), CancerVax (Amgen), and Elan (Perrigo). 

Extensive expertise in Quality Management & Regulatory Affairs, Medical Affairs & Clinical Development, and experience on both the sponsor and CRO. 

Former FDA/CBER reviewer.

SYN023 an Monoclonal Cocktail for Rabies Prophylaxis
Vaccine Innovation Forum World 2025
Eric Tsao
CEO, Synermore Biologics , China

Dr. Eric Tsao has served as the Chief Executive Officer of Synermore Biologics since the founding of the company in 2013.  He has over 25 years of direct experience with more than 20 products in clinical development, four US and EU approved products on the market, and eight biotech manufacturing facilities.  His areas of expertise include biological product development, process design, facility engineering, and operations.  Under his leadership, SYN023, an innovative anti-rabies monoclonal antibody cocktail, has been expertly developed and commercialized for rabies post-exposure prophylaxis.  Since 2008, Dr. Tsao has worked with Morningside Group on biotech investments.  He was instrumental in enhancing portfolio companies’ CMC capabilities. Dr. Tsao was the Vice President of Technical Operations at Aeras, a Gates Foundation sponsored vaccine development organization.  At MedImmune, Dr. Tsao rose to the position of Vice President of Process and Manufacturing Sciences responsible for process development as well as manufacturing of monoclonal antibodies and recombinant vaccines.  The development and manufacturing efforts led to the successful licensing of Synagis, FluMist, and Cervarix.  He was a process development scientist at Johnson & Johnson, where he focused on the development of cell culture processes and start-up of the commercial manufacturing facility for erythropoietin.  Dr. Tsao received his Ph.D. in Chemical Engineering from the University of Michigan.


茶歇
Vaccine clinical development strategy in emerging market(s) and Commercial potentials
Vaccine Innovation Forum World 2025
Adham Rezk
CEO, Celero Global, Singapore

Adham began his professional journey as a neuroscientist, followed by a shift to a commercial career at GSK Vaccines. He possesses over 15 years’ experience in commercialising biological therapeutics in the emerging markets namely Middle East and Africa, South East Asia and South America. He was responsible for obtaining emergency use approval for a prominent Chinese Biotech in the United Arab Emirates prior to China’s Approval. Having led biotech and clinical firms to achieve more than $250 million in revenue over the past 5 years. In addition to having established numerous start- ups, overseeing concept, value proposition, market analysis, business modeling, product development and securing investments. A seasoned health technology expert boasting years of experience in Machine learning and AI in the healthcare space.


Enhancing Vaccine Equity through Global Partnerships and Local Manufacturing: Practices of Chinese Vaccine Manufacturers
Vaccine Innovation Forum World 2025
Meng Li
Director of International Cooperation, Sinopharm CNBG

Meng LI has been leading the International business team of CNBG since 2013, oversees CNBG’s international cooperation and registration activities. She also serves on the board of CNBG-Virogen, and the board of Emerging Biopharmaceuticals Manufacturers Network (EBPMN). During her 19 year experiences in biological industry, she established extensive networks with academia, NGOs, enterprises internationally, and successfully completed a number of landmark projects. Including the bOPV capacity expansion and prequalification program with BMGF (received over 23Million USD financial supports from BMGF, prequalified by WHO in 2019), establishment of CNBG’s first JV with foreign enterprise, the first overseas acquisition by CNBG, roll-out of the Covid-19 vaccine PhIII trials in 6 countries and its registration in over 100 countries. Meng Li has successfully signed a number of in-license, research cooperation, commercialization and industrialization projects with NIH, Oxford, France Institut Pasteur, PATH, IVI, biotech companies and developing country manufacturers. She worked as temporary advisor to WHO inspectorate during WHO’s first inspection to China NMPA in 2010, and was elected as the executive committee member of DCVMN from 2014-2016.


The RIGHT Foundation: Mobilizing Partnerships for Equitable Vaccine Access
Vaccine Innovation Forum World 2025
Hani Kim
Executive Director, The RIGHT Foundation, South Korea

Hani Kim is the Executive Director of the RIGHT (Research Investment for Global Health Technology) foundation, with 16 years of work experience in translational health research as an academic research scientist and at global health R&D funding organizations. She completed her PhD in Lab Medicine and Pathobiology at the University of Toronto, Canada and post-doctoral training in molecular immunology of B cells at the Max-Planck Institute of Immunology, Germany.

During her MPH and her affiliation as a Research Associate at the Johns Hopkins School of Public Health, Hani trained researchers at icddr,b, Bangladesh and KEMRI, Kenya. Prior to joining the RIGHT foundation, she developed and managed portfolios of vaccine discovery grants and molecular surveillance grants as a Gates Fellow initially and later as a Program Officer at the Bill & Melinda Gates Foundation for six years.

Hani has published articles in translational medical research and in the political origins of health inequity. Her recent articles include "The Selangor Consensus: strengthening clinical trials for local public health in the Western Pacific", ‘‘We need people’s WHO to solve vaccine inequity, and we need it now”, “The sociopolitical context of the COVID-19 response in South Korea”, and “A critical assessment of the ideological underpinnings of current practice in global health and their historical origins.”



Chasing the miracles of science through strengthening external partnerships and development of ecosystems
Vaccine Innovation Forum World 2025
Sean Du
Senior Director, External R&D, Sanofi Global R&D Vaccines

As Senior Director at Sanofi Vaccines External R&D, Sean is responsible for the identification and evaluation vaccine-related opportunities to support Sanofi Vaccines’ global pipeline strategy. Under his leadership, Sanofi Vaccines has completed three research agreements, initiated over 10 feasibility studies with both academic and industrial partners, organized 4 full due diligence, executed two global licensing agreements with biotech companies, and reached a 280 million AUD collaboration agreement with Queensland State Government. Sean has over 20 years of extensive vaccine R&D and business development experience. Before joining Sanofi, Sean was Co-Founder and Chief Operating Officer at Altravax from 2013 to 2015 and Executive Director & Head of the Vaccine Research Institute at Simcere Pharmaceutical Group from 2010 to 2013. Prior to Simcere, he worked as a Senior Scientist and Project Leader on multiple vaccine programs at Maxygen for 9 years. Sean received his Ph.D. degree in Biological Sciences from the University of Delaware, M.S degree in Microbiology from the Institute of Microbiology, Chinese Academy of Sciences, and B.S. degree in Microbiology from Shandong University. He received his postdoctoral training at Columbia University.

Innate Immunity and Vaccine Adjuvant Innovation: Leveraging the Body's First Line of Defense
Vaccine Innovation Forum World 2025
Diana Boraschi
Distinguished Professor, Shenzhen Institute of Advanced Technology, China
Diana Boraschi is an immunologist that built her experience in academic institutions and industrial settings in her home country (Italy) and abroad (USA, France, Austria, Korea, Brazil). She is Senior Associate Researcher at the Italian National Research Council (where she served as Institute Director) and at the Stazione Zoologica Anton Dohrn in Napoli, Italy, and Academician of the Accademia dei Fisiocritici. She is currently serving as Distinguished Professor at the Department of Pharmacology at the Shenzhen Institute of Advanced Technologies (SIAT) of the Chinese Academy of Sciences, in Shenzhen, China. She is author of over 200 peer-reviewed research articles in immunology (h-index 67, over 16000 citations), in addition to many books and book chapters, and inventor in eight patents. In 2017, she has received an honorary PhD degree by the University of Salzburg (Austria), in 2020 the High-Level Talents Program Award for Foreign Scholars, and in 2022 the Chinese Government Friendship Award. She is listed within the first 2% scientists worldwide since 2017 and in the first 1% since 2020. Her area of expertise is innate immunity and inflammation, in particular in relation to autoimmune, inflammatory and degenerative diseases, and vaccine development. Her focus on macrophages and cytokines of the IL-1 superfamily (a bioactive IL-1 domain is known as the “Boraschi loop”), and the interaction of engineered nanomaterials with immunity in humans and environmental species. She is particularly involved in higher education training activities in Europe, Asia, Africa, and South America, with a focus on poverty-related diseases.
Vaccine adjuvants, mRNA mode of action, innate/trained immunity for vaccines
Vaccine Innovation Forum World 2025
Robbert van der Most
Former VP, Translational Science, BioNTech/ CEO, VaxxCellence

Dr Robbert van der Most obtained his cum laude PhD in 1994 at Leiden University (Netherlands) on the topic of coronavirus molecular biology. He then conducted postdoctoral work on the immunology of chronic viral infection with Dr Rafi Ahmed(UCLA, Eiory University, USA) and flavivirus molecular biology with Dr Jim Strauss (Caltech, USA). Upon return to the Netherlands he worked on RSV vaccine immunology, focusing on the mechanisms of vaccine-enhanced disease. In 2004, he joined Dr Bruce Robinson's team at the University of Western Australia to study immune oncology and the immune-modifying effects of chemotherapy. In 2008, he joined GSK Vaccines in Belgium, in roles of increasing responsiblility, leadingTranslational Science, After a brief period at CEPl, he joined BioNTech as Vice-President Translational Science in 2022, leading a team of experts in the infectious disease portfolio, in 2024 he started his own consultancy business, aiming to provide scjentific and development advice to biotech and pharma companies, as well as not-for-profit organizations.

TBC
Vaccine Innovation Forum World 2025
Yunlong Cao
Yunlong Cao, Peking University

Yunlong Richard Cao is an immunologist and Assistant Professor at Biomedical Pioneering Innovation Center (BIOPIC), Peking University. Cao obtained B.S. in Physics from Zhejiang University and Ph.D. in Chemistry from Harvard University. Cao’s research focuses on B-cell adaptive immune response, antibody drugs and vaccine designs. During the COVID-19 pandemic, he made key contributions to the understanding of SARS-CoV-2 neutralizing antibodies, humoral immunity of SARS-CoV-2 vaccination and infection, and antibody immune escape of SARS-CoV-2 variants. Cao’s research has been published in Nature, Cell, The Lancet Infectious Diseases and Cell Host & Microbe. Cao is a member of WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) and the Coalition for Epidemic Preparedness Innovations (CEPI) Scientific Advisory Committee. Cao’s work was listed among “China's top 10 scientific advances” and “China's top 10 advances in life sciences” in 2022. Cao was listed among "35 Innovators Under 35" (China) in 2021 by MIT Technology Review and “Ten people who helped shape science in 2022” by Nature (Nature’s 10).


Immunogenicity testing of pan-variant influenza and coronavirus vaccines using pseudotype platform technologies
Vaccine Innovation Forum World 2025
Nigel Temperton
Professor, Director, Viral Pseudotype Unit, University of Kent, UK

Nigel obtained his BSc in Microbiology and Genetics from University College London (UCL) in 1990 and an MSc in Applied Molecular Biology of Infectious Diseases (1992), PhD in Molecular Parasitology (1999) and DLSHTM (2000) from the London School of Hygiene & Tropical Medicine (LSHTM). After his PhD, he returned to UCL as a post-doctoral scientist in the Division of Infection and Immunity. In 2009 Nigel was elected as a member of the highly prestigious Medical Research Club and set up his own research group at the University of Kent. He is currently Chair and Professor in Molecular Virology, Director of the Viral Pseudotype Unit (VPU) and Director of Research and Innovation. Nigel is a Fellow of the Royal Society of Biology (FRSB), Senior Associate Member of the Royal Society of Medicine (RSM), Member of the International Society for Influenza and other Respiratory Virus Diseases (ISIRV), the Microbiology Society and the European Society for Virology (ESV). Nigel acts as external consultant for VisMederi (Italy) and RQbio (UK). He has published over 200 articles with an h-index of 53, >14k citations.


Bioassay for vaccine efficacy
Vaccine Innovation Forum World 2025
Emanuele Montomoli
Co-founder& CSO, VisMederi, Italy
Emanuele Montomoli was graduated in Life Sciences at University of Siena in 1997. Since November 2016 he was appointed by the Department of Molecular Medicine of University of Siena as full Professor on Public Health. Since April 2018 to 2021 he was nominated in the Executive Board of the Toscana Life Sciences Foundation. Since 2010 he he was elected as President of the Board for the “Master in vaccinology and drug development” at University of Siena. Since 2019 he was nominated in the Executive Board of Eurocine vaccines AB. In 2008 he funded VisMederi srl, an enterprise involved in laboratory activities for vaccines and antiviral drugs clinical trials. Actually, he has a role of Chief Scientific Officer in VisMederi srl. Since 1994 he has carried out epidemiological research, surveillance networks for infectious diseases and serological assays for clinical trials for vaccines. In 2015 he was appointed as scientific coordinator for a project funded by EU-IMI (Innovative Medicine Initiative) titled “Standardization and development of assays for assessment of influenza vaccine correlates of protection”. He is the author of more than 200 papers, as well as numerous abstracts and letters, published in international scientific journals.
Antigenic sin drives B cell evolution: lessons learned from the COVID-19 pandemic
Vaccine Innovation Forum World 2025
Emanuele Andreano
Project Leader, Fondazione Toscana Life Sciences, Italy

Dr. Emanuele Andreano is an immunologist with almost 10 years of experience studying B cell and antibody responses to human pathogens, and he is currently project leader at the Monoclonal Antibody Discovery Laboratory (MAD Lab), Fondazione Toscana Life Sciences, directed by his mentor Prof. Rino Rappuoli. During his training, Dr. Andreano gained extensive experience on single cell sorting of memory B cells and isolation, cloning, expression and functional/structural characterization of human monoclonal antibodies. This experience has been used to tackle different pathogens which pose serious threats for global health such as the respiratory syncytial virus (RSV), antimicrobial resistant Neisseria gonorrhoeae, SARS-CoV-2 and more recently the Monkeypox virus. The work that Dr. Andreano performed on SARS-CoV-2 led to the isolation of more than 14,000 thousand human monoclonal antibodies and to the identification of MAD0004J08, one of the most potent monoclonal ever described and evaluated in a phase II/III clinical trial for the treatment of COVID-19. Dr. Andreano first authored publications on top tier journals such as PNAS, Cell, Nature Medicine and Nature. For his scientific work, Dr. Andreano has been awarded the “COVID-19 heroes award” and has been nominated as “Rising Star” in the field of immunology by the International Union of Immunological Societies (IUIS) 2023.

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Advancing One Health: Integrating Veterinary and Human Vaccines to Tackle Global Health Challenges
Vaccine Innovation Forum World 2025
Alejandra Capozzo
Professor, Center Director, Universidad Abierta Interamericana (UAI), Argentina

Dr. Alejandra Capozzo has an MD in Biology from the University of Buenos Aires (UBA), Argentina. She is a Doctor in Biotechnolgy also from the UBA. Her PhD thesis focused on alternative vaccines against foot-and-mouth disease directed by Dr José La Torre. She did postdoctoral studies in neonatal applied immunology at the Center for Vaccine Development (CVD) at University of Maryland (Baltimore, USA), where she worked on the development of new vaccines for neonates in the presence of maternal immunity. She has intensified her training in immunology at the National Academy of Medicine in Buenos Aires, focused on vaccines against Uremic hemolytic syndrome and animal models. Dr Capozzo worked as Market Development Manager for Latin America at Prionics (a Swiss company); and as leader of research and development in Biogenesis-Bagó, an international veterinary vaccine producer. She is also trained in sales management.

From 2008 to 2023 she was the head of the applied veterinary immunology laboratory at the Institute of Virology and Technological Innovations, a CONICET-INTA. She is currently Principal Researcher of the Argentinean national research council (CONICET), the CEO of the Global Foot and Mouth Disease Research Alliance (GFRA), President of the Argentine Association of Veterinary Immunology, coordinator of the Latin American Veterinary Immunology Network, and the Chair of the Veterinary Immunology Committee of the International Union of Immunological societies (VIC-IUIS). Dr Capozzo participates in several transboundary disease groups in FAO-WOAH, as the co-chair of the Global Coordination Committee on Foot and Mouth Disease (GCC-FMD) and as a member of the Partnership and Financial panel (PFP).

Dr Capozzo has been a professor of immunology at the School of Veterinary Medicine of the University of Buenos Aires for many years and directed 14 PhD theses. She is the Responsible Researcher of numerous national and international projects and has developed several products related to applied immunology that were transferred to Argentine and international companies. She is currently the Director of a Center focused on One health, located at the Interamerican University in Buenos Aires, since February 2024.



Trying to hit a moving target: New approaches to porcine reproductive and respiratory syndrome virus vaccine development
Vaccine Innovation Forum World 2025
Simon Graham
Professor, The Pirbright Institute, UK
I am a veterinary immunologist with an interest in understanding mechanisms of protective immunity and its application to vaccine development. My early career focussed on parasitic diseases, I developed a natural cattle model for testing vaccines against onchocerciasis (river blindness), which provided the first proof-of-principle for vaccine-induced protection. I identified and evaluated vaccine candidate antigens from the apicomplexan parasite Theileria parva, which were designed to induce protective bovine CD8 T cell responses. More recently, my research has focussed on porcine viruses, such as classical swine fever (CSFV) and porcine reproductive and respiratory syndrome (PRRSV) viruses. I informed discussions on the use of emergency vaccination to control future CSF outbreaks by demonstrating that live attenuated CSFV prevented transmission of divergent CSFV strains after only 3 days. I showed that this rapid protection was associated with broadly reactive CD8 T cell responses, opening new avenues to develop DIVA vaccines for outbreak settings. For PRRSV, I contributed to the study of the enhanced pathogenicity of Eastern European strains, highlighting the threat these viruses pose; and contributed to vaccine development efforts through the identification of conserved T cell antigens. My current research is largely focussed on PRRSV and we are pursuing complimentary approaches to improved vaccine development. I am also leading research aimed at developing a Nipah virus vaccine for pigs and supporting COVID-19 vaccine development by using the pig as a preclinical model for assessing immunogenicity of vaccine candidates.
Immunological Insights into Animal Disease Control: A Path Toward Enhanced Vaccine Efficacy (TBD)
Vaccine Innovation Forum World 2025
Huichen Guo
Professor, Lanzhou Veterinary Research Institute, China

Dr. Raman Rao joined as the Chief Executive Officer at Hilleman Laboratories in February 2020. Dr. Rao has more than two decades of experience in research and development, manufacturing and commercialisation of vaccines for infectious diseases in global pharma and biotech companies. Prior to joining Hilleman Laboratories, Dr. Rao served as the Vice President of Global Product Operations with Takeda, Singapore, where he enhanced the global product portfolio while successfully leading an international team across Japan, Singapore and the United States. The teams worked in the areas of dengue, norovirus, zika, polio and other vaccines.

Dr. Rao started his career in 2002 with Shantha Biotechnics Limited, part of Sanofi Aventis Group in India, in Clinical Research and Scientific Affairs. He holds a MD in Medical Microbiology from the Postgraduate Institute of Medical Education and Research.

He plans to carry forward Dr. Maurice Hilleman’s legacy for providing effective solutions for global health, especially those impacting low- and middle-income countries.


Development and Application of innovative adjuvants in animal vaccines
Vaccine Innovation Forum World 2025
Huapeng Feng
Associate Professor ,Zhejiang Sci-Tech University, China

Feng Huapeng is an Associate Professor and Master's Supervisor at the ISEEVAX Pharmaceutical Innovation Adjuvant and Novel Animal Vaccine R&D Center, Zhejiang Sci-Tech University. He earned his Ph.D. under the guidance of Academician Professor Chen Hualan, a famous avian influenza expert in China, and completed postdoctoral training at the Institute of Medical Science, the University of Tokyo, Japan. His research focuses on the interaction between influenza viruses and hosts, as well as the development of novel adjuvants.  He has led multiple research projects, including the National Natural Science Foundation of China (NSFC) General Program and the Zhejiang Provincial Natural Science Foundation. To date, he has published 23 SCI-indexed papers, applied for 9 international and national invention patents, and contributed to the development of multiple highly-pathogenic avian influenza vaccines.  Dr. Feng is a member of the Japanese Society for Virology and serves as a Youth Editorial Board Member for *Veterinary Vaccine* and a reviewer for several SCI journals. He has been recognized as a Youth Top Talent of the "City of Distinguished Scholars" Special Support Program in Shaoxing City. Additionally, he has participated in formulating 4 group standards for adjuvants. 


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African swine fever virus antigen discovery
Vaccine Innovation Forum World 2025
Christopher Netherton
Professor, The Pirbright Institute, UK

Chris Netherton leads the African Swine Fever Vaccinology group and has been investigating different aspects of the life cycle of African swine fever virus (ASFV) for over twenty-five years. His studies on ASFV have encompassed analysis of individual viral proteins right through to herd transmission experiments. Chris’ earlier work on ASFV focussed on intracellular virus-host interactions with a strong emphasis on cell-biology.

The principal goal of the research carried out within the ASF Vaccinology group is to support the development of effective vaccines against this devastating disease of domestic pigs. We have identified a pool of eight ASFV genes that prevent severe disease in domestic pigs and aim to improve the protective efficacy of this combination, by characterising immune correlates of protection, identifying additional protective antigens and exploring different vaccine platforms. We are also sequencing Pirbright's reference collection of ASFV isolates to improve our understanding of the genetic diversity of this complex virus and help guide the development of cross-protective vaccines.



Progress and prospect of animal vaccine research and development
Vaccine Innovation Forum World 2025
Jie Li
Head of R&D, Jinyu Baoling Biological Pharmaceutical, China

Li Jie is a doctor from China Agricultural University and a postdoctoral fellow at Cornell University. He serves as the R&D Director of Jinyu Group and is the Director of the Key Laboratory of Ruminant Biological Products under the Ministry of Agriculture. Additionally, he holds the position of Director of the Key Laboratory of Animal Infectious Disease Vaccine and Diagnostic Reagent Engineering Technology in the Inner Mongolia Autonomous Region. Dr. Li specializes in the development of advanced vaccine technologies, including mRNA vaccines, exosome-based vaccines, and AI-driven bioinformatics platforms. He has successfully led the establishment of China's first GMP-compliant production facility for animal mRNA vaccines, which received official approval in February 2024. Under his leadership, the African Swine Fever subunit vaccine and the feline infectious peritonitis mRNA vaccine—both groundbreaking products globally—were submitted for clinical approval in 2024. Dr. Li has integrated cutting-edge technologies such as AI, metagenomics, and bioinformatics to develop a digital vaccine system that enables high-dimensional omics analysis of animal populations across diverse regions. His research focuses on understanding the clinical manifestations of hosts under multi-pathogen conditions post-vaccination and identifying the root causes of vaccine efficacy. Dr. Li has led three key projects at the provincial and municipal levels and has contributed as a sub-project leader to two national key R&D programs. He was awarded first prize in the Eighth China Innovation Challenge Livestock and Swine Technology Competition. With 24 patent applications and over ten peer-reviewed publications.


Progress on the ASF DNA vaccine development in Philippines
Vaccine Innovation Forum World 2025
Frank Chang
CSO, Reber Genetics, China

Dr. Frank Chia-Jung Chang obtains his Ph.D. from Life Science and Institute of Genome Science department of Taiwan Yang-Ming Medical University in 2012. He received his postdoctoral training at Molecular Biology Institute of Academia Sinica (Taiwan) and worked as visiting scholar in Frances H. Arnold’s laboratory (Nobel Prize in Chemistry winner in 2018), Chemical Engineering Department of Caltech (U.S.). He joined Reber Genetics as the supervisor of R&D Division in 2014. From 2017, Frank also works for business development and strategic layout of vaccine products (technology included).

 

Dr. Chang has considerable expertise in virology, microbiology, reverse vaccinology and protein engineering for industrial production. His group has successfully developed novel subunit vaccines of swine PRRSV, pan-PCV, Mycoplasma, CSFV and PEDV in Reber Genetics, furthermore, also support the study of safe vector vaccine against ASF with external partners.


The development of PDCoV and PEDV mRNA vaccines
Vaccine Innovation Forum World 2025
Zhong Chen
Vice President, Suzhou HealiRNA Biotechnology
Doctor of Pharmacy, Postdoctoral Fellow at UNC Chapel Hill, USA. During his academic career, he was awarded the title of Associated Professor. Presided over and/or participated in a number of National Natural Science Foundation projects and national Science and Technology major projects for new drug development, and participated in the successful marketing of small molecule innovative drugs. He has published 20 academic papers in international journals and authorized 10 Chinese invention patents. In the past 5 years, he has focused on the development and industrialization of nucleic acid drug delivery vectors (mRNA, siRNA) and nucleic acid medicinal chemistry, and has applied for a number of PCT patents. He has accumulated a lot of industrialization experience in nucleic acid drug project selection, delivery vector development and CMC research.
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