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Looking back at the development of medicine, we have witnessed the birth of basic small molecule drugs, the vigorous development of antibody drugs such as monoclonal antibody, bispecific antibody, ADC, and so on, and the rise of the "third class of drugs" nucleic acid drugs. Each step marks a great leap in medical technology. Small molecule drugs are innovating against the trend, bringing out the new, and constantly expanding the development space of the industry with new mechanisms, new technologies and new targets. At the same time, ADC/XDC technology has triggered revolutionary changes in key fields such as tumor therapy with its unique dual targeting ability. Nucleic acid drugs, as the third class of drugs after small molecules and antibody drugs, are showing unprecedented potential and broad application prospects in the treatment of genetic diseases, tumors and infectious diseases with their unique molecular mechanisms.
Host by biomap, BPI WEEK 2025 will mark its landmark 10th year, with a continued focus on the frontiers of innovative medicines. We gather industry elites to deeply discuss the latest research trends, technical bottlenecks and market trends of innovative drugs. The core topics covered all important stages of the drug life cycle, such as drug research and development, new target discovery, clinical, process and quality analysis, and commercial development. The conference focuses on industry hotspots and pain points, and is committed to breaking through technical bottlenecks and promoting innovative research and development. After ten years of hard work, our original intention has not changed. We look forward to witnessing a new chapter in the field of innovative medicine with you at BPI WEEK 2025.
周彩存,医学博士,博士生导师,主任医师,教授;上海市领军人才,享受国务院特殊津贴 现任同济大学附属上海市肺科医院肿瘤科主任,医学院肿瘤研究所所长 中国医促会胸部肿瘤分会主委,中国抗癌协会肺癌专业委员会常委,上海市抗癌协会肺癌分子靶向和免疫治疗专业委员会主委,中国抗癌协会肿瘤药物临床研究专业委员会副主任委员,中国医师协会肿瘤分会常委,上海市医师协会肿瘤分会副会长,CSCO理事,上海市医学会肿瘤分会副主任委员 (lung Cancer)副主编,(Translational Lung Cancer Research)主编
张翱,上海交通大学特聘教授,博士生导师,研究组长。2000年在中科院上海有机化学研究所博士毕业,2001-2004年分别在美国乔治敦大学医学中心和哈佛医学院进行博士后研究,2004-2006年担任哈佛医学院讲师。2006年入选中科院“百人计划”回国加盟上海药物研究所,入选上海市浦江人才计划和上海市优秀学科带头人计划,2011年获国家杰出青年科学基金,领衔的研究团队获2018年度科技部“创新人才推进计划”-“重点领域创新团队”称号,2019年获中组部国家“万人计划”领军人才。2020年加入上海交通大学药学院。张翱教授研究团队主要致力于药物化学技术创新推动的新药发现研究,尤其是聚焦基于天然产物的药物化学和化学生物学研究、难靶蛋白的药物设计、分子靶向个性化药物研究等领域。已发表J Am Chem Soc, Angew Chem Int Ed, Chem Sci, J Med Chem,Chem Rev, Pharmacol & Ther等SCI论文170余篇,申请国内国际专利60余项。主持研发的3个1类新药已经进入临床试验研究,多个候选新药正在进行临床前研究。
Dr. Guo-Liang Yu is the global CEO of Apollomics Inc. (Formerly CBT Pharmaceuticals), an innovative therapeutics company devoted to curing cancer by combining immunology and other caner fighting methods. Before Apollomics Inc., Dr. Yu was the Executive Chairman of Crown Biosicence Inc., a publically-listed personalized oncology platform company with ~600 employees globally. Crown Bioscience was acquired by JSR for $400 million in May of 2018. He co-founded Epitomics Inc., an antibody biotechnology company, and served as Chairman and CEO for 10 years prior to its acquisition by Abcam for $170 million. He was also a venture partner at OrbiMed Venture LLC. Dr. Yu’s success is driven by his scientific curiosity and passion for translating scientific discovery to real products. After graduating from Fudan University in Shanghai, China, he came to the United States in 1984 to pursue advanced studies. He obtained his Ph.D. from UC Berkeley, where he and Dr. Greider discovered telomerase and its mechanism in Dr. Blackburn’s lab. Drs. Blackburn and Greider received Nobel Prize in 2009 for their discovery. Dr. Yu later joined Dr. Frederick Ausubel’s lab at Harvard University to pursue the question of how plants defend themselves against pathogens without an immune system, and identified the plant disease resistance gene. In 1993, when genomics was still in its infancy, Dr. Yu joined Human Genome Sciences Inc. as one of the first few senior scientists, identifying human gene targets for drug discovery. Among several important drug targets he studied was BLys, the first successfully genomic target for the development of a lupus antibody drug Benlysta, which was approved by FDA in 2010. In 1998, Dr. Yu was attracted to identifying plant genes with economic value in agriculture and in bio-energy. He was Senior Vice President of R&D at Mendel Biotechnology Inc. where his team analyzed the function of a complete set of plant transcription factors, and ultimately identified several valuable traits such as enhanced crop yield, disease resistance, and drought tolerance. Dr. Yu has co-authored 43 peer-reviewed scientific articles that have been referenced by the scientific community over 6000 times. He is a co-inventor of more than 400 patents. Dr. Yu is the founding president of the Chinese Biopharmaceutical Association (CBA) and serves on the boards of several professional organizations in the United States and China, including BayHelix, Chinese-American Bio/Pharmaceutical Society (CABS), National Foundation of Cancer Research, Ray Wu Memorial Foundation, and University of Pacific. Dr. Yu is generous in coaching young entrepreneurs, and he has co-founded a dozen startup companies in biotech and the healthcare sector, including Immune-Onc Therapeutics, Inc.in Palo Alto.
付博士致力于蛋白降解新药的发现与开发,现任强生(中国)蛋白降解新药发现化学负责人,资深研究员。自2016年起领导和参与了数个PROTAC新药项目和蛋白降解平台建设。付博士于2010年获得中科院上海药物研究所博士学位,同年7月加入美国堪萨斯大学Blake Peterson 教授课题组,进行博士后训练。2013年回国后,先后加入艾伯维(中国)研发中心、强生(中国)研发中心负责创新药研发;在 Angew Chem Int Ed、Cell Chem Biol、 ACS Chem Biol、J Med Chem 等杂志发表论文十余篇,申请发明专利十余项。
张劲涛博士,中国科学院上海有机化学研究所博士,美国芝加哥大学博士后,现任捷思英达医药技术有限公司董事长兼CEO。曾任职美国纳斯达克上市公司DeCode Genetics Inc. (Amgen子公司)和MediChem Research Inc.,部门总监。作为联合创始人成功创办上海美迪西生物医药股份有限公司 (科创版上市企业),任职副总裁及CEO。张劲涛博士专长于抗肿瘤新药的开发研究,具有20多年创新团队管理、研发管线战略规划、国际项目引进和商业化运作的成功经验,他一直致力于肿瘤精准治疗和最前沿的转化医学研究,推动符合中国国情全球化新药开发。张劲涛博士曾荣获中国国家自然科学一等奖。2020年被授予“苏州工业园区第十四届第一批金鸡湖科技领军人才”称号(领军项目)。
赵春林 博士,安龙生物创始人,安龙基金创始合伙人,为清华大学生物系首届毕业生,美国匹兹堡大学医学院分子生物学博士和芝加哥大学工商管理硕士,曾任美国辉瑞制药资深经理,国科嘉和及康桥资本董事总经理,拥有三十多年生命科学及医疗健康领域的创业和投资经验,投资过信达生物,贝瑞合康,天镜生物,歌礼药业,莱凯医药,康乃德及国科恒泰等杰出企业。赵春林博士曾任清华大学生命科学院,医学院及药学院首届校友会主席,为百华协会资深会员。 安龙基金是一只专注于国内早期生命科学与医疗健康领域的基金,投资领域横跨生命科学,医药研发,医疗器械,医疗服务及相关领域。 安龙生物是国内基因治疗及核酸药物领先企业,专注基因新技术及国内大市场产品的新药研发,眼科基因治疗产品已进入临床。 专业之外,赵春林博士喜欢足球,滑雪,曾做过DJ,拥有三个漂亮可爱的女儿。
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